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Magnesium Chloride, Hexahydrate (CAS 7791-18-6)

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Application:
Magnesium Chloride, Hexahydrate is a source of magnesium ion and a co-foactor for many enzymes
CAS Number:
7791-18-6
Purity:
>99%
Molecular Weight:
203.30
Molecular Formula:
MgCl26H2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Magnesium Chloride, Hexahydrate is widely used as a source of magnesium ion in chemistry and molecular biology applications. In biological systems, magnesium is a co-factor for many enzymes including deoxyribonuclease (DNase) and various restriction enzymes. Also plays a role in cell membrane integrity, muscle cell physiology, cardiovascular and muscular activity, and nucleic acid structure. Magnesium chloride solution is a favorable choice as an elution buffer for antibody affinity column purifications; it is much milder on most antigens than acid elution, allowing reuse of the antigen column. Also an essential cofactor for the DNA polymerase in polymerase chain reaction (PCR) amplification.
Anhydrous form also available: Magnesium chloride (sc-255260)


Magnesium Chloride, Hexahydrate (CAS 7791-18-6) References

  1. Polymerase chain reaction in high surface-to-volume ratio SiO2 microstructures.  |  Krishnan, M., et al. 2004. Anal Chem. 76: 6588-93. PMID: 15538781
  2. Main chemical species and molecular structure of deep eutectic solvent studied by experiments with DFT calculation: a case of choline chloride and magnesium chloride hexahydrate.  |  Zhang, C., et al. 2014. J Mol Model. 20: 2374. PMID: 25031082
  3. Properties and uses of restriction endonucleases.  |  Brooks, JE. 1987. Methods Enzymol. 152: 113-29. PMID: 2821353
  4. Trehalose and Magnesium Chloride Exert a Common Anti-amyloidogenic Effect Towards Hen Egg White Lysozyme.  |  Chatterjee, R., et al. 2017. Protein J. 36: 138-146. PMID: 28299593
  5. Crystal structure of a high-pressure phase of magnesium chloride hexahydrate determined by in-situ X-ray and neutron diffraction methods.  |  Yamashita, K., et al. 2019. Acta Crystallogr C Struct Chem. 75: 1605-1612. PMID: 31802749
  6. Metallobiochemistry of the magnesium ion. Characterization of the essential metal-binding site in Escherichia coli ribonuclease H.  |  Huang, HW. and Cowan, JA. 1994. Eur J Biochem. 219: 253-60. PMID: 8306992
  7. [Teratogenicity study of magnesium chloride hexahydrate in rats].  |  Usami, M., et al. 1996. Eisei Shikenjo Hokoku. 16-20. PMID: 9037859
  8. Multiplex PCR: critical parameters and step-by-step protocol.  |  Henegariu, O., et al. 1997. Biotechniques. 23: 504-11. PMID: 9298224
  9. Optimisation of the polymerase chain reaction.  |  Harris, S. and Jones, DB. 1997. Br J Biomed Sci. 54: 166-73. PMID: 9499593
  10. Subunit interactions in the mammalian alpha-ketoglutarate dehydrogenase complex. Evidence for direct association of the alpha-ketoglutarate dehydrogenase and dihydrolipoamide dehydrogenase components.  |  McCartney, RG., et al. 1998. J Biol Chem. 273: 24158-64. PMID: 9727038

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Magnesium Chloride, Hexahydrate, 100 g

sc-203126
100 g
$20.00

Magnesium Chloride, Hexahydrate, 500 g

sc-203126A
500 g
$39.00

Magnesium Chloride, Hexahydrate, 5 kg

sc-203126B
5 kg
$136.00