Date published: 2026-4-24

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Magnesium ascorbyl phosphate (CAS 114040-31-2)

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CAS Number:
114040-31-2
Molecular Weight:
278.39
Molecular Formula:
C6H7O9P•Mg
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Magnesium ascorbyl phosphate is a water-soluble derivative of Vitamin C that functions as an antioxidant in experimental applications. It acts by donating electrons to neutralize free radicals, thereby preventing oxidative damage to cells and biomolecules. This chemical also plays a role in regulating the synthesis of collagen, a crucial protein for maintaining the structural integrity of tissues. In addition, magnesium ascorbyl phosphate has been shown to inhibit the production of melanin, making it a potential ingredient in research related to skin pigmentation. At the molecular level, this compound interacts with reactive oxygen species and enzymes involved in collagen synthesis and melanin production, modulating these processes.


Magnesium ascorbyl phosphate (CAS 114040-31-2) References

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  2. Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and Sodium Ascorbyl Phosphate as used in cosmetics.  |  Elmore, AR. 2005. Int J Toxicol. 24 Suppl 2: 51-111. PMID: 16154915
  3. Development and validation of a reversed-phase ion-pair liquid chromatography method for the determination of magnesium ascorbyl phosphate and melatonin in cosmetic creams.  |  Varvaresou, A., et al. 2006. Anal Chim Acta. 573-574: 284-90. PMID: 17723535
  4. Histopathological, morphometric and stereological studies of ascorbic acid and magnesium ascorbyl phosphate in a skin care formulation.  |  Silva, GM. and Maia Campos, PM. 2000. Int J Cosmet Sci. 22: 169-79. PMID: 18503473
  5. Efficacy of cosmetic formulations containing dispersion of liposome with magnesium ascorbyl phosphate, alpha-lipoic acid and kinetin.  |  Campos, PM., et al. 2012. Photochem Photobiol. 88: 748-52. PMID: 22236139
  6. Magnesium ascorbyl phosphate and coenzyme Q10 protect keratinocytes against UVA irradiation by suppressing glutathione depletion.  |  Hwang, TL., et al. 2012. Mol Med Rep. 6: 375-8. PMID: 22664777
  7. Lauroyl/palmitoyl glycol chitosan gels enhance skin delivery of magnesium ascorbyl phosphate.  |  Wang, PC., et al. 2013. J Cosmet Sci. 64: 273-86. PMID: 23931090
  8. Magnesium Ascorbyl Phosphate Regulates the Expression of Inflammatory Biomarkers in Cultured Sebocytes.  |  Lee, WJ., et al. 2015. Ann Dermatol. 27: 376-82. PMID: 26273151
  9. Efficacy of transdermal magnesium ascorbyl phosphate delivery after ultrasound treatment with microbubbles in gel-type surrounding medium in mice.  |  Liao, AH., et al. 2016. Mater Sci Eng C Mater Biol Appl. 61: 591-8. PMID: 26838887
  10. Effects of Magnesium Ascorbyl Phosphate on the Expression of Inflammatory Biomarkers after Treatment of Cultured Sebocytes with Propionibacterium acnes or Ultraviolet B Radiation.  |  Lee, WJ., et al. 2016. Ann Dermatol. 28: 129-32. PMID: 26848238
  11. Fabrication and characterization of hyaluronic acid microneedles to enhance delivery of magnesium ascorbyl phosphate into skin.  |  Kim, Y., et al. 2019. Biomed Microdevices. 21: 104. PMID: 31773286
  12. Effect of magnesium ascorbyl phosphate on collagen stabilization for wound healing application.  |  Lakra, R., et al. 2021. Int J Biol Macromol. 166: 333-341. PMID: 33122062
  13. Rapid identification of magnesium ascorbyl phosphate utilizing phosphatase through a chromogenic change-coupled activity assay.  |  Wang, Y., et al. 2021. Appl Microbiol Biotechnol. 105: 2901-2909. PMID: 33754168
  14. Stabilization and strengthening of chromium(VI)-contaminated soil via magnesium ascorbyl phosphate (MAP) and phytase addition.  |  Han, L., et al. 2023. J Hazard Mater. 448: 130860. PMID: 36709739
  15. Magnesium ascorbyl phosphate promotes bone formation via CaMKII signaling.  |  Xie, Y., et al. 2023. J Bone Miner Res.. PMID: 37129025

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Magnesium ascorbyl phosphate, 1 g

sc-491852
1 g
$230.00