
MAF1 Antibody (G-5) is a mouse monoclonal IgG1 antibody that detects MAF1 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). MAF1 is a 256 amino acid protein that plays a crucial role in regulating RNA polymerase III activity by interacting with BRF2 to inhibit the assembly of transcription factor TFIIIB onto DNA, thereby repressing the transcription of genes involved in critical cellular processes. This regulation is particularly important as RNA polymerase III is responsible for synthesizing essential small RNAs, including tRNAs and 5S rRNA, which are vital for protein synthesis and cellular function. The gene encoding MAF1 is located on human chromosome 8, a region associated with various diseases, including schizophrenia, bipolar disorder, and certain leukemias, highlighting MAF1′s significance in both normal cellular function and disease pathology. Anti-MAF1 antibody (G-5) provides a valuable tool for researchers studying the intricate mechanisms of gene regulation and potential implications of MAF1 in human health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MAF1 Antibody (G-5) | sc-365312 | 200 µg/ml | $322.00 | |||
MAF1 Antibody (G-5) X | sc-365312 X | 200 µg/0.1 ml | $322.00 |