Molecular structure of Maduramicin Ammonium Salt, CAS Number: 84878-61-5
Maduramicin Ammonium Salt (CAS 84878-61-5)
See product citations (5)
Application:
Maduramicin Ammonium Salt is a polyether antibiotic and antiprotozoal
CAS Number:
84878-61-5
Molecular Weight:
934.16
Molecular Formula:
C47H83NO17
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Maduramicin is a polyether ionophore antibiotic that functions as a coccidiostat in poultry production. It acts by disrupting the transmembrane ion gradients in the mitochondria of coccidia, leading to the collapse of the mitochondrial membrane potential and subsequent cell death. This disruption of ion gradients inhibits ATP synthesis and impairs the function of the electron transport chain, ultimately leading to the death of the coccidia. Maduramicin targets the coccidia and has a narrow spectrum of activity, making it effective against a variety of coccidia species. Its mechanism of action involves binding to and transporting specific ions across the cell membrane, disrupting the normal physiological processes of the coccidia. This disruption ultimately leads to the death of the parasites, making maduramicin an effective for controlling coccidiosis in poultry production.
Maduramicin Ammonium Salt (CAS 84878-61-5) References
- Efficacy of maduramicin ammonium against coccidiosis in turkeys under laboratory and floor-pen conditions. | McDougald, LR., et al. 1990. Avian Dis. 34: 634-8. PMID: 2241692
- Validated spectrophotometric determination of maduramicin ammonium using three charge transfer complexation reactions. | Baker, MM., et al. 2020. Ann Pharm Fr. 78: 388-397. PMID: 32387175
- Modification of the conditions of the authorisation of BioPlus® 2B (Bacillus licheniformis DSM 5749 and Bacillus subtilis DSM 5750) for turkeys for fattening. | , ., et al. 2019. EFSA J. 17: e05726. PMID: 32626348
- Novel Eco-friendly HPLC Methods Using Refractive Index Detector for Analysis of Three Veterinary Antibiotics in Pharmaceutical Formulations and Rat Plasma. | Gamal, M. and Elhalim, LMA. 2020. J Chromatogr Sci. 58: 940-950. PMID: 32901249
- Assessment of the feed additive consisting of Enterococcus faeciumDSM 7134 (Bonvital®) for chickens for fattening for the renewal of its authorisation (Lactosan GmbH & Co. KG). | , ., et al. 2021. EFSA J. 19: e06451. PMID: 33732397
- Safety and efficacy of an additive consisting of Bacillus amyloliquefaciens DSM 25840 for all animal species (Chr. Hansen A/S). | , ., et al. 2021. EFSA J. 19: e06522. PMID: 33897861
- Safety and efficacy of an additive consisting of Bacillus subtilis DSM 32324 for all animal species (Chr. Hansen A/S). | , ., et al. 2021. EFSA J. 19: e06523. PMID: 33897862
- Comparative evaluation of single or combined anticoccidials on performance, antioxidant status, immune response, and intestinal architecture of broiler chickens challenged with mixed Eimeria species. | Abdelhady, AY., et al. 2021. Poult Sci. 100: 101162. PMID: 33975034
- Evaluation of the efficacy of maduramacin ammonium in combination with roxarsone and avoparcin in caged broiler chickens. | Berger, H., et al. 1988. Br Poult Sci. 29: 435-8. PMID: 3409087
- Determination of maduramicin ammonium in poultry feedstuffs by high-performance liquid chromatography. | Gliddon, MJ., et al. 1988. Analyst. 113: 813-6. PMID: 3414970
- Safety and efficacy of a feed additive consisting of Bacillus subtilis FERM BP-07462, Enterococcus lactis FERM BP-10867 and Clostridium butyricum FERM BP-10866 (BIO-THREE®) for chickens for fattening, chickens reared for laying, turkeys for fattening, turkeys reared for breeding, all avian species for rearing/fattening to slaughter and all avian species reared for laying or breeding to point of lay (TOA BIOPHARMA Co., Ltd.). | , ., et al. 2022. EFSA J. 20: e07342. PMID: 35757152
- Optimization of Maduramicin Ammonium-Loaded Nanostructured Lipid Carriers Using Box-Behnken Design for Enhanced Anticoccidial Effect against Eimeria tenella in Broiler Chickens. | Zhang, Y., et al. 2022. Pharmaceutics. 14: PMID: 35890226
- Efficacy of maduramicin against ionophore-tolerant field isolates of coccidia in broilers. | McDougald, LR., et al. 1987. Avian Dis. 31: 302-8. PMID: 3619823
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Maduramicin Ammonium Salt, 100 mg | sc-211759 | 100 mg | $132.00 |