Macrophage Marker Antibody (RM0029-11H3): sc-101447

Macrophage Marker Antibody (RM0029-11H3) is a rat monoclonal IgG2a antibody that detects Macrophage Marker in mouse samples through applications such as immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). Macrophage Marker (RM0029-11H3) antibody is offered in a non-conjugated form, allowing for versatile experimental setups. Macrophages play a crucial role in the immune system as they are responsible for the phagocytosis of pathogens and the clearance of cellular debris, which is vital for maintaining tissue homeostasis and initiating immune responses. These cells are strategically located in various tissues throughout the body, where they can quickly respond to infection or injury. Their ability to adapt to different microenvironments and their plasticity in function enable them to perform diverse roles, from antigen presentation to the secretion of pro-inflammatory cytokines. The dynamic nature of macrophages is essential for both innate and adaptive immunity, as they not only act as first responders to pathogens but also help shape the subsequent immune response, making them a key focus in immunological research and therapeutic development.

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Macrophage Marker Antibody (RM0029-11H3) References:

1. Swine leukocyte antigen and macrophage marker expression on both African swine fever virus-infected and non-infected primary porcine macrophage cultures.  |  Gonzalez Juarrero, M., et al. 1992. Vet Immunol Immunopathol. 32: 243-59. PMID: 1632065
2. Gr-1 antibody induces STAT signaling, macrophage marker expression and abrogation of myeloid-derived suppressor cell activity in BM cells.  |  Ribechini, E., et al. 2009. Eur J Immunol. 39: 3538-51. PMID: 19830733
3. CD68 tumor-associated macrophage marker is not prognostic of clinical outcome in classical Hodgkin lymphoma.  |  Kayal, S., et al. 2014. Leuk Lymphoma. 55: 1031-7. PMID: 24067108
4. An alternatively activated macrophage marker CD163 in severely obese patients: the influence of very low-calorie diet and bariatric surgery.  |  Cinkajzlová, A., et al. 2017. Physiol Res. 66: 641-652. PMID: 28406702
5. Atrial Tissue Pro-Fibrotic M2 Macrophage Marker CD163+, Gene Expression of Procollagen and B-Type Natriuretic Peptide.  |  Watson, CJ., et al. 2020. J Am Heart Assoc. 9: e013416. PMID: 32431194
6. Similar distribution of orally administered eicosapentaenoic acid and M2 macrophage marker in the hypoperfusion-induced abdominal aortic aneurysm wall.  |  Fujishima, R., et al. 2021. Food Funct. 12: 3469-3475. PMID: 33900315
7. PD-1H Expression Associated With CD68 Macrophage Marker Confers an Immune-Activated Microenvironment and Favorable Overall Survival in Human Esophageal Squamous Cell Carcinoma.  |  Chen, Y., et al. 2021. Front Mol Biosci. 8: 777370. PMID: 34950702
8. Integrated analysis of single-cell and bulk RNA sequencing identifies a signature based on macrophage marker genes involved in prostate cancer prognosis and treatment responsiveness.  |  Li, X., et al. 2023. Funct Integr Genomics. 23: 115. PMID: 37010617
9. Identification and exploration of a new M2 macrophage marker MTLN in alveolar echinococcosis.  |  Ma, Y., et al. 2024. Int Immunopharmacol. 131: 111808. PMID: 38457984
10. CNS microvascular pericytes express macrophage-like function, cell surface integrin alpha M, and macrophage marker ED-2.  |  Balabanov, R., et al. 1996. Microvasc Res. 52: 127-42. PMID: 8901442

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Macrophage Marker Antibody (RM0029-11H3) has 21 citations in a variety of scientific publications.

Primary antibodies like Anti-Macrophage Marker Antibody (RM0029-11H3) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Macrophage Marker Antibody (RM0029-11H3) Specifications

Alternate Product Name: Macrophage Marker

Product Clone Name: RM0029-11H3

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a

Amino Acids:

Epitope Target: Macrophage Marker

Epitope Species: mouse

Product Reactivity/Detection: macrophages

Species Reactivity/Detection: mouse

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: IP, IF, IHC(P), FCM

Vialing Information: Each vial contains 100 µg IgG_2a in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 21 citations in various scientific publications

Available Conjugates/Forms for Macrophage Marker Antibody (RM0029-11H3): N/A

The preferred Macrophage Marker antibody is Macrophage Marker Antibody (MAC387): sc-66204.