Macrophage Marker Antibody (ER-MP58): sc-52699

Macrophage Marker Antibody (ER-MP58) is a rat monoclonal IgG2a antibody that detects Macrophage Marker in mouse samples through immunofluorescence (IF) and flow cytometry (FCM) applications. Macrophage Marker (ER-MP58) antibody plays a crucial role in identifying and characterizing macrophages, which are essential components of the immune system. These cells are primarily located in tissues throughout the body, where they perform vital functions such as phagocytosis, antigen presentation, and the secretion of cytokines that modulate immune responses. The strategic positioning of macrophages in various tissues allows them to respond rapidly to pathogens and tissue damage, making them key players in both innate and adaptive immunity. Furthermore, the ability of macrophages to adapt their function based on the local microenvironment underscores their importance in maintaining homeostasis and orchestrating inflammatory responses. By utilizing Macrophage Marker (ER-MP58) monoclonal antibody, researchers can gain insights into macrophage biology, their interactions with other immune cells, and their roles in various disease processes, including infections, autoimmune disorders, and cancer.

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Macrophage Marker Antibody (ER-MP58) References:

1. CD68 tumor-associated macrophage marker is not prognostic of clinical outcome in classical Hodgkin lymphoma.  |  Kayal, S., et al. 2014. Leuk Lymphoma. 55: 1031-7. PMID: 24067108
2. An alternatively activated macrophage marker CD163 in severely obese patients: the influence of very low-calorie diet and bariatric surgery.  |  Cinkajzlová, A., et al. 2017. Physiol Res. 66: 641-652. PMID: 28406702
3. Peritoneal pre-conditioning reduces macrophage marker expression in collagen-containing engineered vascular grafts.  |  Shojaee, M., et al. 2017. Acta Biomater. 64: 80-93. PMID: 28987784
4. M2 Macrophage Marker Chitinase 3-Like 2 (CHI3L2) Associates With Progression of Conventional Renal Cell Carcinoma.  |  Pusztai, C., et al. 2019. Anticancer Res. 39: 6939-6943. PMID: 31810965
5. Atrial Tissue Pro-Fibrotic M2 Macrophage Marker CD163+, Gene Expression of Procollagen and B-Type Natriuretic Peptide.  |  Watson, CJ., et al. 2020. J Am Heart Assoc. 9: e013416. PMID: 32431194
6. Similar distribution of orally administered eicosapentaenoic acid and M2 macrophage marker in the hypoperfusion-induced abdominal aortic aneurysm wall.  |  Fujishima, R., et al. 2021. Food Funct. 12: 3469-3475. PMID: 33900315
7. PD-1H Expression Associated With CD68 Macrophage Marker Confers an Immune-Activated Microenvironment and Favorable Overall Survival in Human Esophageal Squamous Cell Carcinoma.  |  Chen, Y., et al. 2021. Front Mol Biosci. 8: 777370. PMID: 34950702
8. Integrated analysis of single-cell and bulk RNA sequencing identifies a signature based on macrophage marker genes involved in prostate cancer prognosis and treatment responsiveness.  |  Li, X., et al. 2023. Funct Integr Genomics. 23: 115. PMID: 37010617
9. M2 macrophage marker CHI3L2 could serve as a potential prognostic and immunological biomarker in glioma by integrated single-cell and bulk RNA-Seq analysis.  |  Qian, W., et al. 2023. J Gene Med. 25: e3523. PMID: 37147894
10. CNS microvascular pericytes express macrophage-like function, cell surface integrin alpha M, and macrophage marker ED-2.  |  Balabanov, R., et al. 1996. Microvasc Res. 52: 127-42. PMID: 8901442

The preferred Macrophage Marker antibody is Macrophage Marker Antibody (MAC387): sc-66204.