Macrophage Marker Antibody (25F9): sc-52698
- Macrophage Marker Antibody (25F9) is a mouse monoclonal IgG1 provided at 100 µg/ml
- recommended for detection of mature macrophages of human and porcine origin by WB, IF, IHC(P) and FCM
- See Macrophage Marker (MAC387): sc-66204 for Macrophage Marker antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Macrophage Marker Antibody (25F9). This work is in progress.
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Macrophage Marker Antibody (25F9) is a mouse monoclonal IgG1 antibody that detects Macrophage Marker in human and porcine samples through various applications including western blotting (WB), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). Macrophage Marker (25F9) antibody plays a crucial role in identifying macrophages, which are essential components of the immune system, responsible for phagocytosing pathogens and debris, thus maintaining tissue homeostasis. These cells are strategically located in tissues throughout the body, where they can quickly respond to infection or injury. The presence of macrophages in tissues allows for immediate immune responses, as they can recognize and eliminate pathogens without the need for prior sensitization. This rapid response is vital for controlling infections and initiating the healing process, highlighting the importance of Macrophage Marker in both research and clinical settings. Anti-Macrophage Marker antibody (25F9) enables researchers to effectively study macrophage behavior, differentiation, and their interactions with other immune cells, providing insights into various diseases and potential therapeutic targets.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Macrophage Marker Antibody (25F9) References:
- LRP5: A novel anti-inflammatory macrophage marker that positively regulates migration and phagocytosis. | Ma, Y. 2016. J Mol Cell Cardiol. 91: 61-2. PMID: 26739212
- F4/80 as a Major Macrophage Marker: The Case of the Peritoneum and Spleen. | Dos Anjos Cassado, A. 2017. Results Probl Cell Differ. 62: 161-179. PMID: 28455709
- The macrophage marker translocator protein (TSPO) is down-regulated on pro-inflammatory 'M1' human macrophages. | Narayan, N., et al. 2017. PLoS One. 12: e0185767. PMID: 28968465
- The M2 macrophage marker CD206: a novel prognostic indicator for acute myeloid leukemia. | Xu, ZJ., et al. 2020. Oncoimmunology. 9: 1683347. PMID: 32002295
- Vestibular Schwannoma Volume and Tumor Growth Correlates with Macrophage Marker Expression. | Leisz, S., et al. 2022. Cancers (Basel). 14: PMID: 36139588
- Validating a Macrophage Marker Gene Signature (MMGS) in Lung Adenocarcinoma Prognosis and Response to Immunotherapy. | Song, P., et al. J Immunother. 46: 205-215. PMID: 37220007
- Identification and validation of a novel signature based on macrophage marker genes for predicting prognosis and drug response in kidney renal clear cell carcinoma by integrated analysis of single cell and bulk RNA sequencing. | Chen, X., et al. 2024. Aging (Albany NY). 16: 5676-5702. PMID: 38517387
- SFRP1 decreases WNT-Mediated M2 macrophage marker expression in breast tissue. | Gregory, KJ., et al. 2024. Cancer Immunol Immunother. 73: 86. PMID: 38554160
- Bioinformatics Analysis Reveals Prognostic Significance of the Macrophage Marker Gene Signature in Gastric Adenocarcinoma. | Li, Z., et al. 2024. Front Biosci (Landmark Ed). 29: 172. PMID: 38812299
- Identification of a Macrophage marker gene signature to evaluate immune infiltration and therapeutic response in hepatocellular carcinoma. | Li, T., et al. 2024. Heliyon. 10: e31881. PMID: 38845876
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Macrophage Marker Antibody (25F9) | sc-52698 | 100 µg/ml | $322.00 |