Date published: 2026-4-28

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M-cadherin Antibody (12G4): sc-81471

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Datasheets
  • M-cadherin Antibody (12G4) is a mouse monoclonal IgG1, cited in 7 publications, provided at 50 µg/0.5 ml
  • raised against the extracellular domain of M-cadherin of mouse origin
  • recommended for detection of M-cadherin of mouse origin by WB, IP and IF
  • See M-cadherin (C-8): sc-398107 for M-cadherin antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for M-cadherin Antibody (12G4). This work is in progress.
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M-cadherin Antibody (12G4) is a mouse monoclonal IgG1 antibody that detects M-cadherin in mouse samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). M-cadherin is a member of the cadherin family, which plays a crucial role in cell adhesion and is particularly important for the differentiation of skeletal muscle cells. Anti-M-cadherin antibody (12G4) targets proteins primarily located in the plasma membrane of myoblasts and myotubes, where M-cadherin facilitates homophilic interactions essential for muscle cell fusion and tissue integrity. M-cadherin expression notably increases during myotube formation, indicating specific involvement in the development and maintenance of skeletal muscle tissue. Understanding M-cadherin function and localization is vital, as disruptions in expression or function can lead to muscle-related disorders and affect overall muscle regeneration. M-cadherin monoclonal antibody (12G4) serves as an invaluable tool for researchers studying muscle biology and the mechanisms underlying muscle cell differentiation and adhesion.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

M-cadherin Antibody (12G4)

sc-81471
50 µg/0.5 ml
$322.00

For Western Blot, is it recommended to use denatured or non-denatured conditions with M-cadherin (12G4): sc-81471 antibody?

Asked by: jenniferc
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
Answered by: Technical Support
Date published: 2017-03-27
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Rated 4 out of 5 by from Nice WB data with minimal backgroundNice WB data with minimal background -SCBT QC
Date published: 2015-01-20
Rated 5 out of 5 by from Published with it in IF on mouse samplesPublished with it in IF on mouse samples. -SCBT Publication Review
Date published: 2013-11-15
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M-cadherin Antibody (12G4) is rated 4.5 out of 5 by 2.
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