Date published: 2026-4-24

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Lys-(des-Arg9, Leu8)-Bradykinin trifluoroacetate salt (CAS 71800-37-8)

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Alternate Names:
des(Arg10, Leu9)-Kallidin
Application:
Lys-(des-Arg9, Leu8)-Bradykinin trifluoroacetate salt is a B1 bradykinin receptor antagonist
CAS Number:
71800-37-8
Molecular Weight:
998.18
Molecular Formula:
C47H75N13O11
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Lys-(des-Arg9, Leu8)-Bradykinin trifluoroacetate salt is a modified peptide used in biochemical research to study the function and behavior of bradykinin receptors. This particular analog of bradykinin is designed with specific residue substitutions to alter its interaction with bradykinin receptors, providing insight into receptor binding specificity and activation mechanisms. The removal of the Arginine at the ninth position and the replacement of the eighth position with Leucine result in a peptide with distinctive properties compared to the native bradykinin peptide. The trifluoroacetate salt form enhances the solubility of the compound in various solvents, which is beneficial for in vitro experimental setups. Researchers employ Lys-(des-Arg9, Leu8)-Bradykinin trifluoroacetate salt in assays to investigate the physiological pathways regulated by bradykinin and its analogs, such as inflammatory responses and cardiovascular functions.


Lys-(des-Arg9, Leu8)-Bradykinin trifluoroacetate salt (CAS 71800-37-8) References

  1. Bradykinin B1 receptor antagonist protects against cold stress-induced erectile dysfunction in rats.  |  Ruze, A., et al. 2023. Sex Med. 11: qfac004. PMID: 37007851
  2. Expression cloning of a human B1 bradykinin receptor.  |  Menke, JG., et al. 1994. J Biol Chem. 269: 21583-6. PMID: 8063797
  3. Partial agonists and full antagonists at the human and murine bradykinin B1 receptors.  |  MacNeil, T., et al. 1997. Can J Physiol Pharmacol. 75: 735-40. PMID: 9276157
  4. Characterization of bradykinin receptors in human lung fibroblasts using the binding of 3[H][Des-Arg10,Leu9]kallidin and [3H]NPC17731.  |  Zhang, SP. and Codd, EE. 1998. Life Sci. 62: 2303-14. PMID: 9651119

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Lys-(des-Arg9, Leu8)-Bradykinin trifluoroacetate salt, 25 mg

sc-300943
25 mg
$347.00