Date published: 2026-4-4

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Lydicamycin (CAS 133352-27-9)

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Application:
Lydicamycin is an antibiotic with activity against gram-positive bacteria
CAS Number:
133352-27-9
Purity:
>95%
Molecular Weight:
855.11
Molecular Formula:
C47H74N4O10
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Lydicamycin is a compound studied extensively for its unique structural features and biological activity, primarily in the context of natural product chemistry and microbial secondary metabolism. Research involving lydicamycin is often directed toward elucidating the pathways by which it is biosynthesized, which has implications for understanding the genetics and enzymology of antibiotic production in microorganisms. It is also frequently employed as a reference molecule in spectroscopic analysis, such as NMR and mass spectrometry, to aid in the structural characterization of related compounds. Moreover, lydicamycin is of interest in the study of microbial ecology and the interactions between producer organisms and their environment, as compounds like lydicamycin can mediate competitive dynamics within microbial communities. In addition, lydicamycin serves as a starting point for synthetic chemists who are interested in generating novel derivatives with potential biological activities, leveraging its complex molecular architecture to explore chemical space.


Lydicamycin (CAS 133352-27-9) References

  1. LL-49F233alpha, a novel antibiotic produced by an unknown fungus: biological and mechanistic activities.  |  Singh, MP., et al. 1998. J Antibiot (Tokyo). 51: 1109-12. PMID: 10048571
  2. TPU-0037-A, B, C and D, novel lydicamycin congeners with anti-MRSA activity from Streptomyces platensis TP-A0598.  |  Furumai, T., et al. 2002. J Antibiot (Tokyo). 55: 873-80. PMID: 12523820
  3. Clethramycin, a new inhibitor of pollen tube growth with antifungal activity from Streptomyces hygroscopicus TP-A0623. II. Physico-chemical properties and structure determination.  |  Igarashi, Y., et al. 2003. J Antibiot (Tokyo). 56: 705-8. PMID: 14563160
  4. Sch 213766, a novel chemokine receptor CCR-5 inhibitor from Chaetomium globosum.  |  Yang, SW., et al. 2007. J Antibiot (Tokyo). 60: 524-8. PMID: 17827664
  5. Lydicamycin, a new antibiotic of a novel skeletal type. I. Taxonomy, fermentation, isolation and biological activity.  |  Hayakawa, Y., et al. 1991. J Antibiot (Tokyo). 44: 282-7. PMID: 2026553
  6. Lydicamycin, a new antibiotic of a novel skeletal type. II. Physico-chemical properties and structure elucidation.  |  Hayakawa, Y., et al. 1991. J Antibiot (Tokyo). 44: 288-92. PMID: 2026554
  7. Novel anti-infective compounds from marine bacteria.  |  Rahman, H., et al. 2010. Mar Drugs. 8: 498-518. PMID: 20411112
  8. Draft genome sequence of marine-derived Streptomyces sp. TP-A0598, a producer of anti-MRSA antibiotic lydicamycins.  |  Komaki, H., et al. 2015. Stand Genomic Sci. 10: 58. PMID: 26380643
  9. Discovery, properties, and biosynthesis of pseudouridimycin, an antibacterial nucleoside-analog inhibitor of bacterial RNA polymerase.  |  Maffioli, SI., et al. 2019. J Ind Microbiol Biotechnol. 46: 335-343. PMID: 30465105
  10. Antifungal, Plant Growth-Promoting, and Genomic Properties of an Endophytic Actinobacterium Streptomyces sp. NEAU-S7GS2.  |  Liu, D., et al. 2019. Front Microbiol. 10: 2077. PMID: 31551997
  11. Screening of Thiopeptide-Producing Streptomycetes Isolated From the Rhizosphere Soil of Juniperus excelsa.  |  Tistechok, S., et al. 2022. Curr Microbiol. 79: 305. PMID: 36065025
  12. A new neuritogenetic compound BU-4514N produced by Microtetraspora sp.  |  Toda, S., et al. 1993. J Antibiot (Tokyo). 46: 875-83. PMID: 8344867

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Lydicamycin, 500 µg

sc-202216
500 µg
$503.00