Date published: 2026-4-25

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Lycoramine (CAS 21133-52-8)

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Alternate Names:
(4aS,6S,8aR)-4a,5,7,8,9,10,11,12-Octahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol
CAS Number:
21133-52-8
Molecular Weight:
289.37
Molecular Formula:
C17H23NO3
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Lycoramine, an alkaloid naturally found in specific plant parts like leaves, stems, and fruits, belongs to the lycorine group of alkaloids. Its medicinal properties have been extensively researched, both in traditional and modern medicine. Extensive scientific research has explored the potential applications of lycoramine. Notably, it exhibits remarkable anti-inflammatory, anti-oxidant, and anti-cancer properties. Furthermore, it displays promising anti-viral and anti-bacterial effects. Moreover, studies have investigated its ability to hinder the growth of specific fungi and enhance the production of particular enzymes.


Lycoramine (CAS 21133-52-8) References

  1. [Development of intramolecular oxidative phenolic coupling reactions using hypervalent iodine (III) reagents and their application to the synthesis of Amaryllidaceae alkaloids].  |  Arisawa, M., et al. 2000. Yakugaku Zasshi. 120: 1061-73. PMID: 11082716
  2. Lycoris alkaloids, XXV. Studies on the constitution of lycoramine.  |  UYEO, S. and KOIZUMI, J. 1953. Pharm Bull. 1: 202-8. PMID: 13166520
  3. The use of lycoramine derivatives in myasthenia gravis.  |  SOMERS, JE., et al. 1963. Neurology. 13: 543-53. PMID: 13978158
  4. An efficient total synthesis of (+/-)-lycoramine.  |  Fan, CA., et al. 2004. Org Lett. 6: 4691-4. PMID: 15575662
  5. Alkaloids of Lycoris guangxiensis1.  |  Li, HY., et al. 1987. Planta Med. 53: 259-61. PMID: 17269013
  6. Alkaloid accumulation in different parts and ages of Lycoris chinensis.  |  Mu, HM., et al. 2010. Z Naturforsch C J Biosci. 65: 458-62. PMID: 20737914
  7. [Effect of precursor on growth and accumulation of alkaloids of Lycoris radiata suspension cells].  |  Zhang, Y., et al. 2014. Sheng Wu Gong Cheng Xue Bao. 30: 247-54. PMID: 24945053
  8. Formal synthesis of (±)-galanthamine and (±)-lycoramine using Rh(I)-catalyzed [(3 + 2) + 1] cycloaddition of 1-ene-vinylcyclopropane and CO.  |  Feng, Y. and Yu, ZX. 2015. J Org Chem. 80: 1952-6. PMID: 25558884
  9. Profiling of acetylcholinesterase inhibitory alkaloids from some Crinum, Habranthus and Zephyranthes species by GC-MS combined with multivariate analyses and in silico studies.  |  Shawky, E., et al. 2021. Nat Prod Res. 35: 807-814. PMID: 30990078
  10. Total Synthesis of Galanthamine and Lycoramine Featuring an Early-Stage C-C and a Late-Stage Dehydrogenation via C-H Activation.  |  Zhang, Y., et al. 2020. Org Lett. 22: 1244-1248. PMID: 31904968
  11. Evaluation of the Therapeutic Effect of Lycoramine on Alzheimer's Disease in Mouse Model.  |  Kiris, I., et al. 2021. Curr Med Chem. 28: 3449-3473. PMID: 33200692
  12. Total Syntheses of Galanthamine and Lycoramine via a Palladium-Catalyzed Cascade Cyclization and Late-Stage Reorganization of the Cyclized Skeleton.  |  Chang, YP., et al. 2021. Org Lett. 23: 9659-9663. PMID: 34874174
  13. In vitro and in silico analysis of galanthine from Zephyranthes carinata as an inhibitor of acetylcholinesterase.  |  Sierra, K., et al. 2022. Biomed Pharmacother. 150: 113016. PMID: 35483192
  14. Alkaloid Composition and Biological Activities of the Amaryllidaceae Species Ismene amancaes (Ker Gawl.) Herb.  |  Soto-Vásquez, MR., et al. 2022. Plants (Basel). 11: PMID: 35893610
  15. The total synthesis of (+-)-lycoramine. II.  |  Misaka, Y., et al. 1968. J Chem Soc Perkin 1. 23: 2954-9. PMID: 5749970

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Lycoramine, 25 mg

sc-488804
25 mg
$367.00