LY404039 CAS: 635318-11-5
MF: C7H9NO6S
MW: 235.22
A potent agonist of human mGluR-2, mGluR-3 receptors with Ki of 149 nM, and 92 nM respectively.

LY404039 (CAS 635318-11-5)

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Alternate Names: LY2140023
Application: LY404039 is A potent agonist of human mGluR-2, mGluR-3 receptors with Ki of 149 nM, and 92 nM respectively
CAS Number: 635318-11-5
Molecular Weight: 235.22
Molecular Formula: C7H9NO6S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

LY404039 is a potent agonist of recombinant human mGluR-2, mGluR-3 receptors with Ki of 149 nM, and 92 nM respectively. LY404039 suppresses electrically evoked excitatory activity in the striatum, and serotonin-induced L-glutamate release in the prefrontal cortex. LY404039 could modulate glutamatergic activity in limbic and forebrain areas relevant to psychiatric disorders and may be devoid of negative side effects associated with current antipsychotics and anxiolytics.

Physical State :
Solid
Solubility :
Soluble in 30% propylene glycol, 5% Tween 80, 65% D5W (30 mg/ml at 25 °C), DMSO (1 mg/ml at 25 °C), water (< 1 mg/ml at 25 °C), and ethanol (< 1 mg/ml at 25 °C).
Storage :
Store at -20° C
Melting Point :
301.37° C (Predicted)
Boiling Point :
~600.3° C at 760 mmHg (Predicted)
Density :
~1.9 g/cm3 (Predicted)
Refractive Index :
n20D 1.66 (Predicted)
Ki Data :
mGlu2/3: Ki= 88 nM (rat); mGlu3: Ki= 92 nM (human); mGlu2: Ki= 149 nM (human)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
9834591
MDL Number :
MFCD11974011
SMILES :

Download SDS (MSDS)

Certificate of Analysis

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