Ly-GDI/RhoGDI2/ARHGDIB Antibody (E-10): sc-365663

Ly-GDI Antibody (E-10) is a mouse monoclonal IgG3 antibody that detects Ly-GDI in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Ly-GDI, also known as Rho GDIβ, plays a crucial role in regulating the activity of Rho family GTPases, which are essential for various cellular processes, including cell migration, adhesion, and proliferation. By binding to these GTPases, Ly-GDI prevents their activation, thereby modulating signaling pathways that influence cytoskeletal dynamics and cellular responses to external stimuli. Ly-GDI′s function is highlighted by expression primarily in hematopoietic cells, particularly in B and T lymphocyte cell lines, where Ly-GDI helps maintain the balance of GTPase activity necessary for proper immune function. Additionally, Ly-GDI′s interaction with multiple Ras-like GTP-binding proteins, such as Rho A, Rho B, and Cdc42, showcases Ly-GDI′s role as a critical regulator in the intricate network of cell signaling. Ly-GDI antibody (E-10) serves as an invaluable tool for researchers exploring the dynamics of Rho GTPases and their implications in health and disease.

The preferred Ly-GDI/RhoGDI2/ARHGDIB antibody is Ly-GDI/RhoGDI2/ARHGDIB Antibody (G-12): sc-376473.