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LY 78335 is a selective inhibitor of phenylethanolamine-N-methyltransferase (PNMT), an enzyme in the biosynthesis of epinephrine from norepinephrine. This specificity makes LY 78335 a significant compound in neurochemical research, as it allows for detailed study of the catecholamine pathway, which is integral to stress response and neurotransmission. Inhibition of PNMT by LY 78335 has been utilized to probe the regulatory mechanisms governing catecholamine production, offering insights into the physiological and potential pathophysiological roles of epinephrine. The selectivity of LY 78335 also aids in distinguishing the effects of epinephrine relative to other catecholamines, thereby refining our understanding of its function in both the central nervous system and peripheral organs.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
LY 78335, 10 mg | sc-361248 | 10 mg | $260.00 | |||
| US: Only available in the US | ||||||
LY 78335, 50 mg | sc-361248A | 50 mg | $1040.00 | |||
| US: Only available in the US | ||||||