Molecular structure of LY-310,762 hydrochloride, CAS Number: 192927-92-7
LY-310,762 hydrochloride (CAS 192927-92-7)
Alternate Names:
3,3-Dimethyl-1-[2-[4-(4-flurobenzoyl)-1-piperidinyl]-1-ethyl]-1,3-dihydro-2h-indol-2-one hydrochloride
Application:
LY-310,762 hydrochloride is a selective and potent SR-1D antagonist
CAS Number:
192927-92-7
Molecular Weight:
430.94
Molecular Formula:
C24H27FN2O2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
This product is a selective and potent 5-HT1D serotonin receptor antagonist.
LY-310,762 hydrochloride (CAS 192927-92-7) References
- LY367265, an inhibitor of the 5-hydroxytryptamine transporter and 5-hydroxytryptamine(2A) receptor antagonist: a comparison with the antidepressant, nefazodone. | Pullar, IA., et al. 2000. Eur J Pharmacol. 407: 39-46. PMID: 11050288
- Discovery of antagonists of tick dopamine receptors via chemical library screening and comparative pharmacological analyses. | Ejendal, KF., et al. 2012. Insect Biochem Mol Biol. 42: 846-53. PMID: 23213654
- Comparative analysis of pharmacological properties of xanomeline and N-desmethylclozapine in rat brain membranes. | Odagaki, Y., et al. 2016. J Psychopharmacol. 30: 896-912. PMID: 27464743
- A screening campaign in sea urchin egg homogenate as a platform for discovering modulators of NAADP-dependent Ca2+ signaling in human cells. | Gunaratne, GS., et al. 2018. Cell Calcium. 75: 42-52. PMID: 30145428
- Serotonin-Mediated Activation of Serotonin Receptor Type 1 Oppositely Modulates Voltage-Gated Calcium Channel Currents in Rat Sensory Neurons Innervating Hindlimb Muscle. | Anselmi, L., et al. 2022. Mol Pharmacol. 101: 309-321. PMID: 35184045
- Identification of Prazosin as a Potential Flagellum Attachment Zone 1(FAZ1) Inhibitor for the Treatment of Human African Trypanosomiasis. | Orahoske, CM., et al. 2022. ACS Infect Dis. 8: 1711-1726. PMID: 35894227
Inhibitor of:
SR-1D.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
LY-310,762 hydrochloride, 10 mg | sc-300941 | 10 mg | $179.00 |