Molecular structure of Lumula
Lumula
Alternate Names:
Maxeyprost; Unoprostone N-ethyl amide; 7-[3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]-N-ethylhept-5-enamide
Application:
Lumula is used in the study of gaucoma
Molecular Weight:
409.6
Molecular Formula:
C24H43NO4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
A hybrid eicosanoid analog which incorporates the "docosanoid" features of unoprostone as well as the "prostamide" features of bimatoprost.
Lumula References
2 Camras, C.B., Alm, A., Watson, P., et al. Latanoprost, a prostaglandin analog, for glaucoma therapy. Efficacy and safety after 1 year of treatment in 198 patients. Ophthalmology 103 1916-1924 (1996). 3 Woodward, D.F., Krauss, A.H., Chen, J., et al. The pharmacology of Bimatoprost (Lumigan™). Survey of Ophthalmology 45 S337-S345 (2001). 4 Haria, M., Spencer, C.M. Unoprostone (isopropyl unoprostone). Drugs & Aging 9 213-218 (1996). 5 Abramovitz, M., Adam, M., Boie, Y., et al. The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs. Biochim Biophys Acta 1483 285-293 (2000). 6 Maxey, K.M., Johnson, J., Camras, C.B., et al. The hydrolysis of bimatoprost in corneal tissue generates a potent prostanoid FP receptor agonist. Survey of Ophthalmology 47(4) 34-40 (2002). 7 Balapure, A.K., Rexroad, C.E., Kawada, K., et al. Structural requirements for prostaglandin analog interaction with the ovine corpus luteum prostaglandin F2α receptor. Biochem Pharmacol 38 2375-2381 (1989).Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Lumula, 1 mg | sc-221863 | 1 mg | $200.00 | |||
Lumula, 5 mg | sc-221863A | 5 mg | $400.00 |