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Luminol sodium salt (CAS 20666-12-0)

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Alternate Names:
Luminol sodium salt is also known as 3-Aminophthalhydrazide.
Application:
Luminol sodium salt is a chemical that exhibits chemiluminescence, useful for the detection of biological residues.
CAS Number:
20666-12-0
Purity:
98%
Molecular Weight:
199.14
Molecular Formula:
C8H6N3O2Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Luminol sodium salt is a chemical that exhibits chemiluminescence. When mixed with the appropriate oxidizing agent, Luminol sodium salt will have a striking blue glow. Luminol sodium salt is used for chemiluminescence analysis of metal cations, blood and glucococorticoids. This makes Luminol sodium salt an option for crime scene investigation, to detect traces of blood, iron, and hemoglobin. Sensitive ELISA assays are able to be performed with Luminol sodium salt. Luminol sodium salt is also in vivo to picture myeloperoxidase activity.


Luminol sodium salt (CAS 20666-12-0) References

  1. A new copper(II) complex as an efficient catalyst of luminol chemiluminescence.  |  Uzu, T. and Sasaki, S. 2007. Org Lett. 9: 4383-6. PMID: 17880099
  2. 1-Methylnicotinamide and nicotinamide: two related anti-inflammatory agents that differentially affect the functions of activated macrophages.  |  Biedroń, R., et al. 2008. Arch Immunol Ther Exp (Warsz). 56: 127-34. PMID: 18373238
  3. Chemiluminescent detection systems of horseradish peroxidase employing nucleophilic acylation catalysts.  |  Marzocchi, E., et al. 2008. Anal Biochem. 377: 189-94. PMID: 18394418
  4. The ODN probes conjugating the Cu(II) complex enhance the luminol chemiluminescence by assembling on the DNA template.  |  Taniguchi, Y., et al. 2010. Bioorg Med Chem. 18: 8614-7. PMID: 21115284
  5. Development of a highly sensitive chemiluminescence enzyme immunoassay using enhanced luminol as substrate.  |  Tao, X., et al. 2014. Luminescence. 29: 301-6. PMID: 23785024
  6. Chemiluminescent imaging of transpired ethanol from the palm for evaluation of alcohol metabolism.  |  Arakawa, T., et al. 2015. Biosens Bioelectron. 67: 570-5. PMID: 25445620
  7. Extracellular magnesium and calcium blockers modulate macrophage activity.  |  Libako, P., et al. 2016. Magnes Res. 29: 11-21. PMID: 27160489
  8. A new sensitive and quantitative chemiluminescent assay to monitor intracellular xanthine oxidase activity for rapid screening of inhibitors in living endothelial cells.  |  Caliceti, C., et al. 2016. Anal Bioanal Chem. 408: 8755-8760. PMID: 27392750
  9. In Vivo Bioluminescence Imaging for Longitudinal Monitoring of Inflammation in Animal Models of Uveitis.  |  Gutowski, MB., et al. 2017. Invest Ophthalmol Vis Sci. 58: 1521-1528. PMID: 28278321
  10. Ultrasound-mediated drug delivery by gas bubbles generated from a chemical reaction.  |  Lee, S., et al. 2018. J Drug Target. 26: 172-181. PMID: 28693344
  11. In vivo Analysis of Neutrophil Infiltration during LPS-induced Peritonitis.  |  de Almeida, L., et al. 2016. Bio Protoc. 6: PMID: 28752106
  12. 3-Aminophthalhydrazide (Luminol) As a Matrix for Dual-Polarity MALDI MS Imaging.  |  Li, B., et al. 2019. Anal Chem. 91: 8221-8228. PMID: 31149814
  13. Detection of nitric oxide production from a perfused organ by a luminol-H2O2 system.  |  Kikuchi, K., et al. 1993. Anal Chem. 65: 1794-9. PMID: 8368532

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Luminol sodium salt, 1 g

sc-218662
1 g
$102.00

Luminol sodium salt, 5 g

sc-218662A
5 g
$270.00

How long does luminol last in -20C?

Asked by: Hagit
Thank you for your question. Manufacturing, expiration, and retest dates are not provided on our Certificates of Analysis for list products, although, all of our products are warrantied for one year from the date purchased. We suggest to retest the quality of the chemical every year.
Answered by: Technical Support
Date published: 2017-03-15

What are the recommended storage conditions for a constituted luminol salt solution? How long would it stay potent in -20C?

Asked by: Hagit
Thank you for your question. We recommend to use solutions of Luminol sodium salt (CAS 20666-12-0) the same day they are made. If you need to store the solution, we recommend to aliquot into useable amounts and store in the dark at -20º C.
Answered by: Technical Support
Date published: 2017-02-26

What is the appearance of the chemical?

Asked by: two2igm05
Thank you for your question. Luminol sodium salt, sc-218662, is a light-yellow powder in its appearance.
Answered by: TechService7
Date published: 2017-01-03
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Rated 5 out of 5 by from Tseng et alTseng et al. (PubMed ID 23978851) used Luminol sodium salt to visualize neutrophil phagocytes across inflammatory phases by reacting with superoxides produced within neutrophils. -SCBT Publication Review
Date published: 2015-06-18
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Luminol sodium salt is rated 5.0 out of 5 by 1.
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