Molecular structure of Luminol, CAS Number: 521-31-3
Luminol (CAS 521-31-3)
See product citations (37)
Alternate Names:
3-Aminophthalhydrazide
Application:
Luminol is a chemiluminescence generating reagent for biological and metal cation assays
CAS Number:
521-31-3
Purity:
≥97%
Molecular Weight:
177.16
Molecular Formula:
C8H7N3O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Luminol is a reagent for the generation of chemiluminescence in biological assays including nitric oxide and myeloperoxidase assay. Luminol is converted to a dianion in basic solution, which is then oxidized with H2O2/Cu2+ to form N2 and an aminophthalate ion in an electronically excited state. The aminophthalate ion emits a photon of wavelength 424 nm. Luminol-enhanced chemiluminescence is highly sensitive and is the basis for many of the enhanced chemiluminescent (ECL) reagents used in Western blot detection systems. It′s favored for its ability to detect low-abundance proteins, making it a staple in laboratories performing protein analysis.
Luminol (CAS 521-31-3) References
- Illuminating the health and safety of luminol. | Larkin, T. and Gannicliffe, C. 2008. Sci Justice. 48: 71-5. PMID: 18700499
- On the fluorescence of luminol in a silver nanoparticles complex. | Voicescu, M. and Ionescu, S. 2013. J Fluoresc. 23: 569-74. PMID: 23463296
- Luminol-based chemiluminescent signals: clinical and non-clinical application and future uses. | Khan, P., et al. 2014. Appl Biochem Biotechnol. 173: 333-55. PMID: 24752935
- Electrochemiluminescence Bioassays with a Water-Soluble Luminol Derivative Can Outperform Fluorescence Assays. | Mayer, M., et al. 2018. Angew Chem Int Ed Engl. 57: 408-411. PMID: 29119667
- 3-Aminophthalhydrazide (Luminol) As a Matrix for Dual-Polarity MALDI MS Imaging. | Li, B., et al. 2019. Anal Chem. 91: 8221-8228. PMID: 31149814
- Luminol-Based Turn-On Fluorescent Sensor for Selective and Sensitive Detection of Sulfur Mustard at Ambient Temperature. | Singh, VV., et al. 2021. Anal Chem. 93: 1193-1199. PMID: 33289388
- G-quadruplex-forming aptamer enhances the peroxidase activity of myoglobin against luminol. | Tsukakoshi, K., et al. 2021. Nucleic Acids Res. 49: 6069-6081. PMID: 34095949
- Enhanced Cathodic Electrochemiluminescence of Luminol on Iron Electrodes. | Feng, M., et al. 2021. Anal Chem. 93: 16425-16431. PMID: 34843226
- Single-Atom Iron Enables Strong Low-Triggering-Potential Luminol Cathodic Electrochemiluminescence. | Gu, W., et al. 2022. Anal Chem. 94: 9459-9465. PMID: 35734950
- Ratiometric Electrochemiluminescence Sensing of Carcinoembryonic Antigen Based on Luminol. | Shang, L., et al. 2022. Anal Chem. 94: 12845-12851. PMID: 36067524
- Luminol-induced neutrophil chemiluminescence. | Allred, CD., et al. 1980. Biochim Biophys Acta. 631: 380-5. PMID: 7407252
- Luminol and lucigenin as detectors for O2.-. | Faulkner, K. and Fridovich, I. 1993. Free Radic Biol Med. 15: 447-51. PMID: 8225026
- Peroxynitrite-induced luminol chemiluminescence. | Radi, R., et al. 1993. Biochem J. 290 (Pt 1): 51-7. PMID: 8382481
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Luminol, 5 g | sc-362181 | 5 g | $27.00 | |||
Luminol, 25 g | sc-362181A | 25 g | $68.00 | |||
Luminol, 100 g | sc-362181C | 100 g | $200.00 | |||
Luminol, 500 g | sc-362181B | 500 g | $702.00 | |||
Luminol, 1 kg | sc-362181D | 1 kg | $1230.00 |