LRP1B Antibody (164C2U): sc-517611
- LRP1B Antibody (164C2U) is a mouse monoclonal IgG1 κ provided at 100 µg/ml
- raised against recombinant LRP1B of human origin
- recommended for detection of LRP1B of human origin by WB
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for LRP1B Antibody (164C2U). This work is in progress.
LRP1B Antibody (164C2U) is a mouse monoclonal IgG1 antibody that detects LRP1B in human samples through western blotting (WB). LRP1B, a member of the low-density lipoprotein receptor (LDLR) gene family, plays a crucial role in mediating the endocytosis of extracellular ligands, particularly in the regulation of the transmembrane protein beta-amyloid precursor protein (APP). The proteolytic processing of APP leads to the production of Amyloid-beta peptide, a key player in the pathogenesis of Alzheimer′s disease, highlighting LRP1B′s importance in neurodegenerative processes. Additionally, LRP1B is involved in the catabolism of the platelet-derived growth factor beta-receptor, which influences the migration of smooth muscle cells and implicates LRP1B in the development of atherosclerosis, a condition that poses significant risks to cardiovascular health. Furthermore, LRP1B has been identified as a critical factor in the tumorigenesis of non-small cell lung cancer, making LRP1B a significant target for research in cancer biology. Anti-LRP1B antibody (164C2U) is an essential tool for researchers investigating the multifaceted roles of LRP1B in various diseases.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
LRP1B Antibody (164C2U) | sc-517611 | 100 µg/ml | $322.00 |