LRP1B Antibody (1642CT736.5.59): sc-517340
- LRP1B Antibody (1642CT736.5.59) is a mouse monoclonal IgG1 κ provided at 100 µg/ml
- raised against a recombinant protein corresponding to amino acids 2620-2891 of LRP1B of human origin
- recommended for detection of LRP1B of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for LRP1B Antibody (1642CT736.5.59). This work is in progress.
LRP1B Antibody (1642CT736.5.59) is a mouse monoclonal IgG1 antibody that detects LRP1B in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). LRP1B, a member of the low-density lipoprotein receptor (LDLR) gene family, plays a crucial role in the endocytic trafficking of the beta-amyloid precursor protein (APP), which is essential for the regulation of amyloid-beta peptide production. The accumulation of amyloid-beta is a significant factor in the development of Alzheimer′s disease, making LRP1B a key player in neurodegenerative processes. Additionally, LRP1B is involved in the catabolism of the platelet-derived growth factor beta-receptor, which influences smooth muscle cell migration and is implicated in the pathogenesis of atherosclerosis, a condition that can lead to serious cardiovascular issues. Furthermore, LRP1B has been identified as an important factor in the tumorigenesis of non-small cell lung cancer, highlighting its relevance in cancer research. Anti-LRP1B antibody (1642CT736.5.59) provides valuable insights into these critical biological processes, serving as an essential tool for researchers studying the mechanisms underlying these diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
LRP1B Antibody (1642CT736.5.59) | sc-517340 | 100 µg/ml | $316.00 |