Date published: 2025-12-5

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LRGILS-NH2 (CAS 245329-01-5)

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CAS Number:
245329-01-5
Molecular Weight:
656.83
Molecular Formula:
C29H56N10O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Reversed amino acid sequence control peptide for SLIGRL-NH2 (sc-359903), a protease-activated receptor-2 (PAR2) agonist that facilitates gastrointestinal transit in vivo.


LRGILS-NH2 (CAS 245329-01-5) References

  1. Evidence that PAR-1 and PAR-2 mediate prostanoid-dependent contraction in isolated guinea-pig gallbladder.  |  Tognetto, M., et al. 2000. Br J Pharmacol. 131: 689-94. PMID: 11030717
  2. Proteinases and proteinase-activated receptor 2: a possible role to promote visceral hyperalgesia in rats.  |  Coelho, AM., et al. 2002. Gastroenterology. 122: 1035-47. PMID: 11910355
  3. Protease-activated receptor-2 stimulates angiogenesis and accelerates hemodynamic recovery in a mouse model of hindlimb ischemia.  |  Milia, AF., et al. 2002. Circ Res. 91: 346-52. PMID: 12193468
  4. Modulation of capsaicin-evoked visceral pain and referred hyperalgesia by protease-activated receptors 1 and 2.  |  Kawao, N., et al. 2004. J Pharmacol Sci. 94: 277-85. PMID: 15037813
  5. Protease-activated receptor-2 (PAR-2)-related peptides induce tear secretion in rats: involvement of PAR-2 and non-PAR-2 mechanisms.  |  Nishikawa, H., et al. 2005. J Pharmacol Exp Ther. 312: 324-31. PMID: 15331653
  6. Stimulation of PAR-2 excites and sensitizes rat cutaneous C-nociceptors to heat.  |  Ding-Pfennigdorff, D., et al. 2004. Neuroreport. 15: 2071-5. PMID: 15486484
  7. Initial support for the hypothesis that PAR2 is involved in the immune response to Nippostrongylus brasiliensis in mice.  |  Devlin, MG., et al. 2007. Parasitol Res. 101: 105-9. PMID: 17458579
  8. Protease-activated receptor 2 activation inhibits N-type Ca2+ currents in rat peripheral sympathetic neurons.  |  Kim, YH., et al. 2014. Mol Cells. 37: 804-11. PMID: 25410909
  9. Effect of the house dust mite allergen Der p 1 on tryptase release from human mast cells.  |  Wang, DQ., et al. 2016. Genet Mol Res. 15: PMID: 27421012
  10. Small Intestine Protection of Mica Against Non-Steroidal Anti-Inflammatory Drugs-Injury Through ERK1/2 Signal Pathway in Rats.  |  Zhang, S., et al. 2019. Front Pharmacol. 10: 871. PMID: 31427976

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

LRGILS-NH2, 1 mg

sc-361979
1 mg
$155.00