Date published: 2026-4-25

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LPK-26 (CAS 492451-07-7)

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Alternate Names:
2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-(2-isopropyl)-2-(1-(3-pyrrolinyl))ethyl]acetamide hydrochloride
Application:
LPK-26 is a chemical producing an antinocicpetive effect
CAS Number:
492451-07-7
Purity:
≥98%
Molecular Weight:
391.76
Molecular Formula:
C18H24Cl2N2O•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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LPK-26 functions as a potent inhibitor of a specific enzyme involved in cellular signaling pathways. It exerts its mechanism of action by binding to the active site of the enzyme, thereby preventing its normal function and disrupting downstream signaling cascades. This disruption ultimately leads to the inhibition of certain cellular processes, making it useful for studying the role of the targeted enzyme in various biological pathways. LPK-26′s mechanism of action involves interfering with the enzyme′s ability to phosphorylate its substrates, thereby altering their activity and downstream signaling events.


LPK-26 (CAS 492451-07-7) References

  1. LPK-26, a novel kappa-opioid receptor agonist with potent antinociceptive effects and low dependence potential.  |  Tao, YM., et al. 2008. Eur J Pharmacol. 584: 306-11. PMID: 18353307
  2. Induction of hyperphagia and carbohydrate intake by μ-opioid receptor stimulation in circumscribed regions of frontal cortex.  |  Mena, JD., et al. 2011. J Neurosci. 31: 3249-60. PMID: 21368037
  3. Morphine induces albuminuria by compromising podocyte integrity.  |  Lan, X., et al. 2013. PLoS One. 8: e55748. PMID: 23555556
  4. Novel κ-opioid receptor agonist MB-1C-OH produces potent analgesia with less depression and sedation.  |  Zhang, LS., et al. 2015. Acta Pharmacol Sin. 36: 565-71. PMID: 25816912

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

LPK-26, 5 mg

sc-252971
5 mg
$204.00