Molecular structure of Loxapine, Succinate, CAS Number: 27833-64-3
Loxapine, Succinate (CAS 27833-64-3)
Alternate Names:
Loxapine succinate salt
Application:
Loxapine, Succinate is a D2DR, D4DR, and serotonin inhibitor
CAS Number:
27833-64-3
Purity:
≥98%
Molecular Weight:
445.90
Molecular Formula:
C22H24ClN3O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Loxapine, Succinate is a compound used in research related to neurotransmitter pathways and receptor dynamics. Studies often focus on its interactions with dopamine and serotonin receptors due to its affinity for these sites in the central nervous system. Research utilizing Loxapine, Succinate includes investigations into receptor binding properties, signal transduction mechanisms, and the regulation of neurotransmitter release. Additionally, the compound is of interest in the study of neuronal pathways that may influence behavior and cognitive functions. Loxapine, Succinate also serves as a tool in examining the biochemistry of receptor subtypes and their role in neuronal communication, as well as the overall function of neurochemical systems.
Loxapine, Succinate (CAS 27833-64-3) References
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- Factors associated with initiation on clozapine and on other antipsychotics among Medicaid enrollees. | Manuel, JI., et al. 2012. Psychiatr Serv. 63: 1146-9. PMID: 23117514
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- A complementary experimental and computational study of loxapine succinate and its monohydrate. | Bhardwaj, RM., et al. 2013. Acta Crystallogr C. 69: 1273-8. PMID: 24192171
- Success of tardive electroconvulsive therapy sessions after loxapine-induced malignant syndrome in the context of very poor metabolisation. | Descoeur, J., et al. 2017. Therapie. 72: 643-647. PMID: 28647110
- The in Vitro Actions of Loxapine on Dopaminergic and Serotonergic Receptors. Time to Consider Atypical Classification of This Antipsychotic Drug? | Ferreri, F., et al. 2018. Int J Neuropsychopharmacol. 21: 355-360. PMID: 29106549
- Investigation of the photolysis and TiO2, SrTiO3, H2O2-mediated photocatalysis of an antipsychotic drug loxapine - Evaluation of kinetics, identification of photoproducts, and in silico estimation of properties. | Trawiński, J., et al. 2018. Chemosphere. 204: 1-10. PMID: 29635095
- Development and validation of an HPLC-UV method for analysis of methylphenidate hydrochloride and loxapine succinate in an activated carbon disposal system. | Bakshi, P., et al. 2018. J Pharm Anal. 8: 349-356. PMID: 30595940
- Toxicity of designer benzodiazepines: A case of etizolam and cocaine intoxication. | Drevin, G., et al. 2022. Forensic Sci Int. 336: 111324. PMID: 35525006
- Fifty years of experience with loxapine for the rapid non-coercive tranquilization of acute behavioral disturbances in schizophrenia patients, and beyond. | Nuss, P., et al. 2022. Expert Rev Neurother. 22: 639-653. PMID: 35913401
- Loxapine succinate: a double-blind comparison with haloperidol and placebo in acute schizophrenics. | Selman, FB., et al. 1976. Curr Ther Res Clin Exp. 19: 645-52. PMID: 819222
- Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype. | Shen, Y., et al. 1993. J Biol Chem. 268: 18200-4. PMID: 8394362
- The role of the 5-HT2A and 5-HT2C receptors in the stimulus effects of hallucinogenic drugs. I: Antagonist correlation analysis. | Fiorella, D., et al. 1995. Psychopharmacology (Berl). 121: 347-56. PMID: 8584617
Inhibitor of:
D2DR, D4DR, SR-2A, and SR-2B.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Loxapine, Succinate, 500 mg | sc-211754 | 500 mg | $189.00 |