LONRF1 Antibody (4G7): sc-101123
- LONRF1 Antibody (4G7) is a mouse monoclonal IgA LONRF1 antibody provided at 100 µg/ml
- raised against recombinant LONRF1 of human origin
- recommended for detection of LONRF1 of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for LONRF1 Antibody (4G7). This work is in progress.
LONRF1 Antibody (4G7) is a mouse monoclonal IgA antibody that detects LONRF1 protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-LONRF1 antibody (4G7) is available as a non-conjugated format. LONRF1 protein, also known as RNF191, is a 416 amino acid protein characterized by the presence of a LON domain and a RING-type zinc finger domain, which plays a crucial role in the ubiquitination pathway, a key mechanism for protein degradation and regulation within the cell. The RING-type zinc finger motif, which is a conserved cysteine-rich domain capable of binding two zinc atoms, facilitates interaction with E3 ubiquitin ligases, thereby influencing the stability and turnover of various target proteins. This interaction maintains cellular homeostasis and regulates processes such as cell cycle progression, apoptosis, and response to stress. LONRF1 (4G7) antibody enables researchers to gain insights into the functional dynamics of LONRF1 and its implications in cellular processes.
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LONRF1 Antibody (4G7) References:
- RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination. | Lorick, KL., et al. 1999. Proc Natl Acad Sci U S A. 96: 11364-9. PMID: 10500182
- 8p23.1 duplication syndrome; a novel genomic condition with unexpected complexity revealed by array CGH. | Barber, JC., et al. 2008. Eur J Hum Genet. 16: 18-27. PMID: 17940555
- Comparative FISH-mapping of twelve loci in river buffalo and sheep chromosomes: comparison with HSA8p and HSA4q. | Perucatti, A., et al. 2007. Cytogenet Genome Res. 119: 242-4. PMID: 18253036
- New insights into the role of the ubiquitin-proteasome pathway in the regulation of apoptosis. | Liu, CH., et al. 2007. Chang Gung Med J. 30: 469-79. PMID: 18350730
- The RING finger domain: a recent example of a sequence-structure family. | Borden, KL. and Freemont, PS. 1996. Curr Opin Struct Biol. 6: 395-401. PMID: 8804826
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
LONRF1 Antibody (4G7) | sc-101123 | 100 µg/ml | $339.00 |