Lithocholic acid 3-sulfate disodium salt (CAS 64936-81-8)

Lithocholic acid 3-sulfate disodium salt emerges from its progenitor molecule, lithocholic acid, a constituent of bile with a pivotal role in the digestive process, specifically in the emulsification and assimilation of fats. This compound serves as an invaluable asset within the scientific community, primarily employed as a reference standard or as an instrument to elucidate the complex pathways of bile acid metabolism and functionality. Its multifaceted biological activities underscore its significance in research focused on lipid homeostasis. By activating the pregnane X receptor (PXR), a key regulator in the xenobiotic detoxification process, it offers insights into the body′s defense mechanisms against potentially harmful compounds. Moreover, its capability to induce apoptosis in cancer cells positions it as a critical tool in the study of mechanisms underlying cell death and survival, providing a gateway to understanding the intricacies of cancer biology and potentially guiding the development of novel therapeutic strategies targeting malignancies. Through these roles, lithocholic acid 3-sulfate disodium salt not only advances our knowledge of bile acid functions but also contributes to broader research areas concerning lipid metabolism and the molecular foundations of disease.