Lithium beta-hydroxypyruvate CAS: 3369-79-7
MF: C3H3LiO4
MW: 109.99
A substrate for transketolase.

Lithium β-hydroxypyruvate (CAS 3369-79-7)

Lithium β-hydroxypyruvate, CAS 3369-79-7 is rated 5.0 out of 5 by 1.
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Alternate Names: hydroxypyruvic acid
Application: Lithium β-hydroxypyruvate is a substrate for transketolase
CAS Number: 3369-79-7
Purity: >97%
Molecular Weight: 109.99
Molecular Formula: C3H3LiO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Lithium β-hydroxypyruvate is a substrate for transketolase, and used for the production of optically pure L-2-hydroxy aldehydes.


References

1. Y. Kobori et al. J. Org. Chem. 57, 5899, (1992) 2. F. Effenberger et al. Tetrahedron Lett. 33, 5157, (1992)

Appearance :
Powder
Physical State :
Solid
Storage :
Store at room temperature
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
23675243
MDL Number :
MFCD10567214
SMILES :
[O-]C(=O)C(=O)CO.O.[Li+]

Download SDS (MSDS)

Certificate of Analysis

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sc-252955 is a lithium salt, rather than a sodium salt, is it appropriate for use in the enzyme assay for hydroxypyruvate reductase? I am concerned as to whether the lithium could interact.

Asked by: ChemSynth123
Thank you for your question. Lithium β-hydroxypyruvate (CAS 3369-79-7): sc-252955 is appropriate for used as a standard assay mixture for hydroxypyruvate reductase.
Answered by: Chemical Support 7
Date published: 2017-03-07
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Rated 5 out of 5 by from Yi Yi, D. et al. (PubMed 23001740) developed a pH-based high-throughput assay method for the rapid and reliable measurement of transketolase activity. The method is based on the decarboxylation of Lithium -hydroxypyruvate as a hydroxyacetyl donor with an aldehyde acceptor, using phenol red as the pH indicator. Upon release of carbon dioxide from Lithium -hydroxypyruvate, the pH increase in the reaction mixture can be determined photometrically by the color change of the pH indicator. -SCBT Publication Review
Date published: 2015-07-08
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