LPS: sc-21855. Western blot analysis of Dhh expression in untreated (A), Pervanadate treated (B), Anisomycin-treated (C), LPS and IFN-γ-treated (D) and PMA-treated (E) K-562 whole cell lysates. Detection reagent used: m-IgG2a BP-HRP: sc-542731. β-Actin (C4): sc-47778 used as loading control. Detection reagent used: m-IgG1 BP-HRP: sc-525408. Antibody tested: Dhh (A-12): sc-133244.
Lipopolysaccharide, E. coli O55:B5 (CAS 93572-42-0)
See product citations (12)
Alternate Names:
Lipopolysaccharide, E. coli O55:B5 is also known as LPS E. coli O55:B5.
Application:
Lipopolysaccharide, E. coli O55:B5 is a component of the cell wall of Gram-negative bacteria and Specific activator of Toll-like receptor (TLR) 4.
CAS Number:
93572-42-0
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Lipopolysaccharide, E. coli O55:B5 is a component of the cell wall of the O55:B5 serotype of the Gram-negative bacteria, Escherichia coli. Lipopolysaccharides (LPS) are made up of a hydrophobic lipid, a hydrophilic core polysaccharide chain and a hydrophilic O-antigenic polysaccharide side chain. LPS molecules contribute to the outer integrity of the cell membrane, protect the cell against bile salts and lipophilic antibiotics, and act as endotoxins in animals. LPS induces a strong immune response by binding to the CD14/TLR4/MD2 receptor complex, which promotes the secretion of pro-inflammatory cytokines. LPS is also an exogenous pyrogen. Lipopolysaccharide, E. coli O55:B5 is used to activate toll-like receptor 4 (TLR4) on leukocytes, eliciting inflammatory signaling in isolated cells. Lipopolysaccharide, E. coli O55:B5 includes three regions, the O-antigenic polysaccharide chain, the core oligosaccharide, and lipid A. Lipopolysaccharide, E. coli O55:B5 stimulates the activity of inducible nitric oxide synthase. Lipopolysaccharide, E. coli O55:B5 induces apoptosis in mouse thymus and swine lymphocytes.
Lipopolysaccharide, E. coli O55:B5 (CAS 93572-42-0) References
- Endotoxin-induced lung inflammation is independent of the complement membrane attack complex. | Brauer, RB., et al. 2000. Infect Immun. 68: 1626-32. PMID: 10678982
- Postovulatory effect of intravenous administration of lipopolysaccharide (E. coli, O55:B5) on the contractile activity of the oviduct, ova transport, binding of accessory spermatozoa to the zona pellucida and embryo development in sows. | Mwanza, AM., et al. 2002. Reprod Domest Anim. 37: 269-74. PMID: 12354178
- Lipopolysaccharide from Rhodobacter sphaeroides is an agonist in equine cells. | Lohmann, KL., et al. 2003. J Endotoxin Res. 9: 33-7. PMID: 12691616
- Aggregation behavior and size of lipopolysaccharide from Escherichia coli O55:B5. | Bergstrand, A., et al. 2006. Colloids Surf B Biointerfaces. 53: 9-14. PMID: 16934960
- Specific Lipopolysaccharide Serotypes Induce Differential Maternal and Neonatal Inflammatory Responses in a Murine Model of Preterm Labor. | Migale, R., et al. 2015. Am J Pathol. 185: 2390-401. PMID: 26212908
- Suppression of Dendritic Cell-Derived IL-12 by Endogenous Glucocorticoids Is Protective in LPS-Induced Sepsis. | Li, CC., et al. 2015. PLoS Biol. 13: e1002269. PMID: 26440998
- Sevoflurane Preconditioning Prevents Septic Myocardial Dysfunction in Lipopolysaccharide-Challenged Mice. | Li, J., et al. 2019. J Cardiovasc Pharmacol. 74: 462-473. PMID: 31425341
- Effect of lipopolysaccharide on nitric oxide synthase activity in rat proximal tubules. | Mayeux, PR., et al. 1995. Biochem Pharmacol. 49: 115-8. PMID: 7530953
- Pentamethyl-hydroxychromane, vitamin E derivative, inhibits induction of nitric oxide synthase by bacterial lipopolysaccharide. | Hattori, S., et al. 1995. Biochem Mol Biol Int. 35: 177-83. PMID: 7537570
- Norepinephrine suppresses inducible nitric oxide synthase activity in rat astroglial cultures. | Feinstein, DL., et al. 1993. J Neurochem. 60: 1945-8. PMID: 7682604
- In vivo induction of apoptosis (programmed cell death) in mouse thymus by administration of lipopolysaccharide. | Zhang, YH., et al. 1993. Infect Immun. 61: 5044-8. PMID: 8225580
- Serum factors, cell membrane CD14, and beta2 integrins are not required for activation of bovine macrophages by lipopolysaccharide. | Jungi, TW., et al. 1997. Infect Immun. 65: 3577-84. PMID: 9284122
Inhibitor of:
3β-hsd1, A1-d, Arp9, B7-H6, BTBD18, Cdc24, Cdc25, claudin-1, cyclin 2b, cyclin 3a, cyclin 3b, hnRNP X, IFN-γR2, IL-11Rα1, IL-11Rα2, LYSMD2, OPG, TREML4, and UCP2.Activator of:
α Enolase, α-defensin 6, β thromboglobulin, β-defensin 111, β-defensin 119, β-defensin 12, β-defensin 121, β-defensin 123, β-defensin 125, β-defensin 126, β-defensin 127, β-defensin 128, β-defensin 134, β-defensin 135, β-defensin 136, β-defensin 137, β-defensin 15, β-defensin 32, β-defensin 46, β-defensin 5, β-defensin 7, 6CKine, ADX, AIM2, AOAH, AP1, APP, ASK 1, AT2, azurocidin, B Cell Marker, B lymphocytes, B7-1, B7RP-1, Baff, BAT4, BATF2, BCAP, Bcl-3, Bcl10, BCRF1, BID, Blimp-1, Bmi-1, BPIL3, BRAP, BRCC3, Brt, Btk, c-Rel, C/EBP δ, C1orf77, C1qL1, C3a, C3b, C3d, C4a, C4orf26, C5orf30, C8α, C8β, Cactin, Calgranulin A, Calgranulin B, cathepsin 3, Cbl, Cbl-b, CCL12, CCL15, CCL16, CCL23, CD1, CD137, CD14, CD16, CD16-2, CD163L1, CD1A, CD1B, CD1E, CD209b, CD209c, CD209d, CD209e, CD225, CD27L, CD2BP2, CD300LB, CD300LD, CD40, CD47, CD48, CD5L, CD62L ligand, CD66E, CD8α, CD8β, CD83, CEACAM3, CINC-1, CKLF, CKR-5, CL-P1, CLCA, CLEC-1, CLEC-12A, CLEC-12B, CLEC-18A, CLEC-3A, CLEC-4F, CLEC-5A, CLEC-9A, CLP24, Clusterin-L1, CMTM2b, Collectin 43, Conglutinin, Coronavirus surface antigen, cPLA2, CRAMP, CRP, CRTAM, Cst9, CTAP-III, CTLA-2α, CTXL, CXCR-3, cyclin D2, CysLT1, CYTIP, DC Marker, DDX60, Dendritic Cell marker, Dok-1, DsRed, E-Selectin, EG240921, EG432555, EG436336, EG626682, EG667977, Elmo, EMAP II, EMMPRIN, Emp, eotaxin-3, Epilysin, Ezrin, FBL19, FcRH1, FcRH2, FcRH4, Fcrl5, FCRLM1, FDC-SP, Follicular DC Marker, fractalkine, Fragilis, G-CSF, Gads, galectin-10, GBP2, GBP4, GBP5, GBP7, GCET1, GDE3, GGPL-I, GGPL-III, GILT, GM-CSF, GM-CSFR, GODZ, Granulocytee Marker, granzyme C, granzyme G, granzyme K, GRK 2, GRO, GROα_KC, GROβ, group IIE sPLA2, group X sPLA2, H2-Ab, H2-Dk, H2-Kd, H2-Kk, H2-Kk,p,q,r,s, H60a, Hairy Cell Leukemia Marker, HCC-1, HCC-3, HCC-4, HEATR3, Hep G NS3, HepC NS3, HepC NS4a, HepC NS5a, HepC NS5b, HepG NS3, HHV-4 EBNA-2, HHV-4 LMP-1, HHV-4 ZEBRA, HIV GAG, HIV vpr, HLA-3, HLA-D, HLA-DR, HLA-HB1, HLX1, HMG-1, HNP, HNP-3, HSV-1 Glycoprotein D, IκB-ζ, IAP, Iba1, ICAM-1, ICAM-4, ICOS, IDO, IFI-16, IFI-35, IFN-α13, IFN-γ, Ig κ, Ig λ chain V4A, IgA2, IgD Chain, IgG, IgG κ light chain, IgG λ light chain, IgG Fab fragment, IgG light chain, IgG2a, IgG2b, IgG2c, IgH, IgH-VJ558, IgHg, Igk-C, Igkv3-4, IL-1α, IL-12, IL-12A p35, IL-12B p70, IL-13Rα2, IL-15, IL-16, IL-17B, IL-17D, IL-17F, IL-17REL, IL-19, IL-1F10, IL-1F6, IL-1RI, IL-1Rrp2, IL-26, IL-8, ILT-1, ILT-6, Integrin αM, Integrin β4, IQGAP1, IRF-1, IRF-7, IRG1, JAM-B, KIR2DL4, KLRF1, KLRG1, KSHV ORF 57, Ku-86, kynurenine, LA-PF4, LAIR-2, LECT2, Leukocyte Marker, LILRC1, Lipocalin-13, LITAF, LL-37, LMO4, LPAP, LPLUNC3, LRP1, LRP3, LRRFIP2, LST1, Ly-6C, LYSMD4, M-ficolin, Mac-3, Macrophage Subset, Macrophagee Marker, MALAT-1, MASP-2, Mast Cell Chymase, Mast Cell Protease 7, MATE1, Max, MCP-2, MDC, Mdr-2, megsin, MFG-E8, Mfn1, MGMT, MHC class I, MHC class II DQ, MHC class II I E, MIF, MIP-1α, MIP-1β, MIP-1γ, MIP-1b, MIP-2, MIP-2α, MIP-3α, MIP-3β, MIP-4, MIP-5, ML-IAP, MLK3, MMD, MMP-13, MMP-3, MPO, Mucin 5AC, MuRF1, MXRA8, MYH7B, N-Ras, N-SMase, NAIP2, NAIP5, NAIP6, NAIP7, NALP4, NALP6, NALP9, NCK1, Nef, Neutrophil Elastase, NFκB p52, NFκB p65, NF2, NIK, Ninjurin-1, NK 2B4, NOD2, NOD3, OAS1, OLFM3, Olfr961, Olfr963, Optineurin, OTTMUSG00000003605, OTTMUSG00000011269, OTTMUSG00000017866, P-Rex2, P-Selectin, p38β, p67-phox, PAC-1, PADI1, PAFAH1B3, PAP-2a, PC-PLD2, PDF, PDK2, Pellino 2, PGE synthase 2, PGRP-Iα, PGRP-S, PI 3-kinase p110δ, PKC θ, PLC γ2, PLEKHQ1, PLSCR1, Polyoma virus VP1, POP2, PRAM-1, PSG20, PSTPIP2, PTP1B, PU.1, Qa-2, RANTES, REG IIIα, Reg IIIγ, REGIIIα, RelA, Rheumatoid Factor, Rho A, Ribosomal Protein S6, RICK, RNase 6, RNase 7, RNF135, RNF17, RNF183, rotavirus C vp4, rotavirus NSP4, rotavirus vp7, RT1-A, RT1-Ac, RT1-Bα, SAAL1, SARM, SEB, SerpinA3g, SHARPIN, Siglec-1, Siglec-14, Siglec-15, Siglec-L1, SIRP-α1, SIRP-β1b, SIRT2, SLAMF6, Smad3, SPAG11B, SphK1, Spi-B, SPPL2a, SRCRB4D, SREC, SSAT, SSNA1, T-bet, T-cell receptor Vδ 2, TAB1, TALL-1, TAP, TARM1, TCR V α 8, TGTP, Thrombin R, TICAM-1, TICAM-2, Tif, TIM-3, TIM-4, TLF, TLR1, TLR13, TLR4, TLR6, TMEM143, TNF-IP 1, TNF-R1, TNF-R2, TNFβ, TOX3, TRABID, Tracheobronchial Mucin, TRAF3, TRAF6, TREM-1, TREM-2a, TREM-2b, TREM-2c, TRIM11, TRIM34, TRIM34B, TRIM43A, TRIM5α, TRIM52, TRIM56, TSG-6, TSLP, TSLPR, TWEAK, Vav, VpreB3, Yersinia pestis F1, Ym1, ZC3H12B, ZDHHC1, ZNF683, ZPI, and ZSCAN4.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Lipopolysaccharide, E. coli O55:B5, 10 mg | sc-221855 | 10 mg | $96.00 | |||
Lipopolysaccharide, E. coli O55:B5, 25 mg | sc-221855A | 25 mg | $166.00 | |||
Lipopolysaccharide, E. coli O55:B5, 100 mg | sc-221855B | 100 mg | $459.00 | |||
Lipopolysaccharide, E. coli O55:B5, 500 mg | sc-221855C | 500 mg | $1615.00 |