Linolenic Acid ethyl ester (CAS 1191-41-9)

Linolenic acid ethyl ester (LAEE) is a neutral, more lipophilic form of the free acid that can be used as an exogenous source of α-linolenic acid (ALA). Linolenic acid ethyl ester increases cyclin E expression and Cdk2 activity, as well as extracellular-signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) activity.

References

1. Allman, M A., et al., 1995. Supplementation with flaxseed oil versus sunflowerseed oil in healthy young men consuming a low fat diet: effects on platelet composition and function. European journal of clinical nutrition. 49(3): 169-78. PMID: 7774533

2. Li, Jianjun., et al., 2003. The ethanol metabolite, linolenic acid ethyl ester, stimulates mitogen-activated protein kinase and cyclin signaling in hepatic stellate cells. Life sciences. 73(9): 1083-96. PMID: 12818718