Linoleic Acid-d4 (CAS 79050-23-0)

Linoleic Acid-d4, cataloged under CAS number 79050-23-0, is a deuterated form of linoleic acid, an essential polyunsaturated fatty acid predominantly involved in various biological functions. This modified version of linoleic acid incorporates deuterium atoms, replacing the hydrogen atoms, which makes it particularly useful in research for tracing and studying metabolic pathways involving fatty acids without altering their chemical nature. The incorporation of deuterium atoms increases the molecular stability and changes the vibrational modes of the molecule, which are detectable using spectroscopic methods such as NMR (nuclear magnetic resonance) and mass spectrometry. Linoleic Acid-d4 is extensively used in studies to understand the metabolic fate of linoleic acid in living organisms and in various cellular systems. It helps researchers track the enzymatic conversion of linoleic acid into other bioactive metabolites, such as arachidonic acid, and its further metabolism into eicosanoids. This deuterated compound is crucial for elucidating the detailed mechanisms of lipid metabolism, the regulation of cellular signaling pathways, and the interactions between fatty acids and other cellular constituents. By using Linoleic Acid-d4, researchers can gain precise insights into the dynamics of lipid incorporation into cell membranes, the generation of lipid mediators, and the overall impact of fatty acids on cellular function and health.