Linoleic acid-¹³C18 (CAS 287111-25-5)

Linoleic acid-13C18, with the CAS number 287111-25-5, is a stable isotope-labeled form of linoleic acid, where all the carbon atoms are replaced with the carbon-13 (^13C) isotope. This modification makes it an essential tool in research, particularly in the study of lipid metabolism and the complex biochemical pathways involving fatty acids. Linoleic acid, a polyunsaturated omega-6 fatty acid, is crucial in numerous biological processes, and tracing its metabolic route using the ^13C-labeled version allows for detailed analysis without altering the chemical nature of the molecule. This isotopic labeling is valuable for researchers utilizing mass spectrometry, as it provides clearer, more distinct peaks that differentiate from the non-labeled forms, thus enabling precise tracking of linoleic acid incorporation into cellular lipids and its conversion into other metabolites. Linoleic acid-13C18 is also used in studies focusing on lipid oxidation, where the impact of oxidative stress on cellular mechanisms can be traced more accurately. This can lead to a better understanding of the role of fatty acids in cell membrane integrity and function. Additionally, this labeled compound helps in elucidating the dietary intake of linoleic acid and its subsequent distribution and storage in biological tissues, providing insights into nutritional science and metabolic regulation.