Date published: 2026-4-24

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Linear B trisaccharide (CAS 101627-01-4)

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Alternate Names:
Gal-a-1,3Gal-b-1,4GlcNAc
CAS Number:
101627-01-4
Molecular Weight:
545.49
Molecular Formula:
C20H35NO16
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Linear B trisaccharide is extensively utilized in glycobiology research due to its structure and functional properties. This synthetic oligosaccharide is composed of a sequence of three sugar molecules, often used as a model to study carbohydrate-protein interactions that are crucial in numerous biological processes, including cell signaling and molecular recognition. Its specific composition enables researchers to dissect the complex details of glycan binding and specificity, providing insights into how sugars affect protein function at a molecular level. Linear B trisaccharide serves as an important tool in the study of lectins, a type of protein that binds carbohydrates specifically and non-covalently, playing a pivotal role in cellular communication and pathogen recognition. The chemical′s utility extends to the development of glycoconjugates, where it is used to modify proteins or surfaces to study interactions within biological systems or to enhance the stability of biologically active molecules. By contributing to a clearer understanding of glycosylation patterns, this trisaccharide aids in elucidating the roles of carbohydrates in complex biological systems, thereby emphasizing its significance in fundamental scientific research.


Linear B trisaccharide (CAS 101627-01-4) References

  1. Synthesis of linear-B saccharopeptides via enzymatic galactosylation of non-natural glucosamide acceptors.  |  Schwardt, O., et al. 2001. Bioorg Med Chem. 9: 1857-69. PMID: 11425588
  2. Thermodynamic analysis of the binding of galactose and poly-N-acetyllactosamine derivatives to human galectin-3.  |  Bachhawat-Sikder, K., et al. 2001. FEBS Lett. 500: 75-9. PMID: 11434930
  3. The mushroom Marasmius oreades lectin is a blood group type B agglutinin that recognizes the Galalpha 1,3Gal and Galalpha 1,3Galbeta 1,4GlcNAc porcine xenotransplantation epitopes with high affinity.  |  Winter, HC., et al. 2002. J Biol Chem. 277: 14996-5001. PMID: 11836253
  4. Synthesis and characterization of a novel glycopolymer with protective activity toward human anti-alpha-Gal antibodies.  |  Vetere, A., et al. 2002. Glycobiology. 12: 283-90. PMID: 12042251
  5. Carbohydrates and derivatives as potential drug candidates with emphasis on the selectin and linear-B area.  |  Ohrlein, R. 2001. Mini Rev Med Chem. 1: 349-61. PMID: 12369962
  6. Removal of anti-Galalpha1,3Gal xenoantibodies with an injectable polymer.  |  Katopodis, AG., et al. 2002. J Clin Invest. 110: 1869-77. PMID: 12488437
  7. In vivo neutralization of naturally existing antibodies against linear alpha(1,3)-galactosidic carbohydrate epitopes by multivalent antigen presentation: a solution for the first hurdle of pig-to-human xenotransplantation.  |  Duthaler, RO., et al. 2010. Chimia (Aarau). 64: 23-8. PMID: 21137679
  8. The carbohydrate-binding promiscuity of Euonymus europaeus lectin is predicted to involve a single binding site.  |  Agostino, M., et al. 2015. Glycobiology. 25: 101-14. PMID: 25209582
  9. Evidence that intravenously administered alpha-galactosyl carbohydrates reduce baboon serum cytotoxicity to pig kidney cells (PK15) and transplanted pig hearts.  |  Ye, Y., et al. 1994. Transplantation. 58: 330-7. PMID: 8053057
  10. On the preparative use of recombinant pig alpha(1-3)galactosyl-transferase.  |  Baisch, G., et al. 1998. Bioorg Med Chem Lett. 8: 1575-8. PMID: 9873393

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Linear B trisaccharide, 1 mg

sc-286135
1 mg
$184.00

Linear B trisaccharide, 2 mg

sc-286135A
2 mg
$408.00