Molecular structure of LF3, CAS Number: 664969-54-4
LF3 (CAS 664969-54-4)
Alternate Names:
CHEMBL5185515 N-[4-(Aminosulfonyl)phenyl]-4-(3-phenyl-2-propenyl)-1-piperazinecarbothioamide
CAS Number:
664969-54-4
Molecular Weight:
416.60
Molecular Formula:
C20H24N4O2S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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LF3 (CAS 664969-54-4) References
- Defective flagellar assembly and length regulation in LF3 null mutants in Chlamydomonas. | Tam, LW., et al. 2003. J Cell Biol. 163: 597-607. PMID: 14610061
- A Small-Molecule Antagonist of the β-Catenin/TCF4 Interaction Blocks the Self-Renewal of Cancer Stem Cells and Suppresses Tumorigenesis. | Fang, L., et al. 2016. Cancer Res. 76: 891-901. PMID: 26645562
- A small-molecule LF3 abrogates β-catenin/TCF4-mediated suppression of NaV1.5 expression in HL-1 cardiomyocytes. | Zhao, L., et al. 2019. J Mol Cell Cardiol. 135: 90-96. PMID: 31419437
- Small-molecule inhibitor LF3 restrains the development of pulmonary hypertension through the Wnt/β-catenin pathway. | Lei, Y., et al. 2021. Acta Biochim Biophys Sin (Shanghai). 53: 1277-1289. PMID: 34410330
- Rta is the principal activator of Epstein-Barr virus epithelial lytic transcription. | Ali, A., et al. 2022. PLoS Pathog. 18: e1010886. PMID: 36174106
- β-catenin/TCF4 inhibitors ICG-001 and LF3 alleviate BDL-induced liver fibrosis by suppressing LECT2 signaling. | Gao, Y., et al. 2023. Chem Biol Interact. 371: 110350. PMID: 36639009
Inhibitor of:
Bcl-9, Dapper1, frizzled-8, LOC666145, mPRβ, POP-1, Pygopus 2, R-Spondin4, TBL1XR1, TCF-19, TCF-4, TNIK, and Wnt-1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
LF3, 10 mg | sc-507526 | 10 mg | $160.00 |