Molecular structure of Levalbuterol Hydrochloride, CAS Number: 50293-90-8
Levalbuterol Hydrochloride (CAS 50293-90-8)
Alternate Names:
(R)-Albuterol Hydrochloride; Xopenex
Application:
Levalbuterol Hydrochloride is a β2-adrenoceptor agonist
CAS Number:
50293-90-8
Molecular Weight:
275.77
Molecular Formula:
C13H21NO3•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Levalbuterol Hydrochloride is a selective beta2-adrenergic receptor agonist that functions by binding to beta2-adrenergic receptors on airway smooth muscle cells. This binding activates the enzyme adenylate cyclase, which catalyzes the conversion of adenosine triphosphate (ATP) to cyclic adenosine monophosphate (cAMP). The increased levels of cAMP leads to the activation of protein kinase A, which phosphorylates and activates various proteins involved in the relaxation of smooth muscle cells. This mechanism of action at the molecular level allows for the investigation of its effects on cellular signaling pathways and the potential modulation of smooth muscle cell function in experimental contexts.
Levalbuterol Hydrochloride (CAS 50293-90-8) References
- Levalbuterol: pharmacologic properties and use in the treatment of pediatric and adult asthma. | Berger, WE. 2003. Ann Allergy Asthma Immunol. 90: 583-91; quiz 591-2, 659. PMID: 12839314
- Compatibility of budesonide inhalation suspension with four nebulizing solutions. | McKenzie, JE. and Cruz-Rivera, M. 2004. Ann Pharmacother. 38: 967-72. PMID: 15084687
- In vitro estimations of in vivo jet nebulizer efficiency using actual and simulated tidal breathing patterns. | Bosco, AP., et al. 2005. J Aerosol Med. 18: 427-38. PMID: 16379618
- Solid-state characterization of two polymorphic forms of R-albuterol sulfate. | Palacio, MA., et al. 2007. J Pharm Biomed Anal. 43: 1531-4. PMID: 17141446
- Chemical and physical compatibility of levalbuterol inhalation solution concentrate mixed with budesonide, ipratropium bromide, cromolyn sodium, or acetylcysteine sodium. | Bonasia, PJ., et al. 2008. Respir Care. 53: 1716-22. PMID: 19025708
- Efficacy of Inhaled Levalbuterol Compared to Albuterol in Horses with Recurrent Airway Obstruction. | Arroyo, MG., et al. 2016. J Vet Intern Med. 30: 1333-7. PMID: 27282625
- Levalbuterol lowers the feedback inhibition by dopamine and delays misfolding and aggregation in tyrosine hydroxylase. | Flydal, MI., et al. 2021. Biochimie. 183: 126-132. PMID: 33309753
Activator of:
beta2-AR.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Levalbuterol Hydrochloride, 10 mg | sc-396448 | 10 mg | $95.00 | |||
Levalbuterol Hydrochloride, 50 mg | sc-396448A | 50 mg | $365.00 |