Molecular structure of Leukotriene F4, CAS Number: 83851-42-7
Leukotriene F4 (CAS 83851-42-7)
Alternate Names:
5S-hydroxy-6R-(S-γ-glutamylcysteinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid
Application:
Leukotriene F4 is a cysteinyl-leukotriene exhibiting agonistic properties
CAS Number:
83851-42-7
Molecular Weight:
568.72
Molecular Formula:
C28H44N2O8S
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Leukotriene F4 (LTF4) is a cysteinyl-leukotriene produced in vitro, but not reported to date in vivo. It is formed by the incubation of LTE4 with γ-glutamyl transpeptidase and glutathione, where it is a weak agonist in its ability to contract vascular smooth muscle. The rank order of potency of the cysteinyl-leukotrienes to contract vascular smooth muscle is LTD4 > LTC4 > LTE4 >> LTF4.
Leukotriene F4 (CAS 83851-42-7) References
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- Crocetin Prolongs Recovery Period of DSS-Induced Colitis via Altering Intestinal Microbiome and Increasing Intestinal Permeability. | Feng, P., et al. 2022. Int J Mol Sci. 23: PMID: 35409192
- Effect of acetone fraction of Ottelia alismoides on the G2/M cell cycle arrest and apoptosis in the human carcinoma cell lines. | Das, S., et al. 2023. J Ethnopharmacol. 300: 115729. PMID: 36162544
- An integrated fecal microbiome and metabolome in rats reveal variations in gut microbiota and fecal metabolic phenotype of Semen Euphorbiae and Semen Euphorbiae Pulveratum. | Wei, X., et al. 2022. J Chromatogr B Analyt Technol Biomed Life Sci. 1211: 123459. PMID: 36209673
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- Psoraleae Fructus Ethanol Extract Induced Hepatotoxicity via Impaired Lipid Metabolism Caused by Disruption of Fatty Acid β-Oxidation. | Guo, Z., et al. 2023. Oxid Med Cell Longev. 2023: 4202861. PMID: 36647431
- Leukotriene F4 and the release of arachidonic acid metabolites from perfused guinea pig lungs in vitro. | Lord, A., et al. 1985. Prostaglandins. 29: 651-60. PMID: 3923570
- Synthesis and biological activities of leukotriene F4 and leukotriene F4 sulfone. | Denis, D., et al. 1982. Prostaglandins. 24: 801-14. PMID: 6300970
- Leukotrienes D4 and E4 produced in myocardium impair coronary flow and ventricular function after two hours of global ischaemia in rat heart. | Lee, CC., et al. 1993. Cardiovasc Res. 27: 770-3. PMID: 8394207
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Leukotriene F4, 25 µg | sc-205371 | 25 µg | $143.00 | |||
Leukotriene F4, 50 µg | sc-205371A | 50 µg | $267.00 |