Molecular structure of Leukotriene B4-d4, CAS Number: 124629-74-9
Leukotriene B4-d4 (CAS 124629-74-9)
Alternate Names:
5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraenoic acid-d4
Application:
Leukotriene B4-d4 is an internal standard for the quantification of LTB4 by GC- or LC-mass spectrometry
CAS Number:
124629-74-9
Molecular Weight:
340.50
Molecular Formula:
C20H28D4O4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Leukotriene B4-d4 is a lipid mediator that plays a role in the inflammatory response. It is involved in the activation and chemotaxis of leukocytes, particularly neutrophils, at the site of inflammation. This chemical functions by binding to specific receptors on the surface of leukocytes, triggering a signaling cascade that leads to the release of pro-inflammatory cytokines and the amplification of the immune response. Leukotriene B4-d4 also promotes the adhesion of leukocytes to the endothelium, facilitating their migration into the inflamed tissue. At the molecular level, this chemical modulates the activity of various enzymes and transcription factors involved in the regulation of inflammatory pathways. Its mechanism of action involves the activation of intracellular signaling pathways, leading to the production of reactive oxygen species and the release of inflammatory mediators.
Leukotriene B4-d4 (CAS 124629-74-9) References
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- Omega-6 and Omega-3 Fatty Acid-Derived Oxylipins from the Lipoxygenase Pathway in Maternal and Umbilical Cord Plasma at Delivery and Their Relationship with Infant Growth. | Thompson, M., et al. 2022. Int J Mol Sci. 23: PMID: 35054892
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- Altered mucosal and plasma polyunsaturated fatty acids, oxylipins, and endocannabinoids profiles in Crohn's disease. | Ben-Mustapha, Y., et al. 2023. Prostaglandins Other Lipid Mediat. 168: 106741. PMID: 37149256
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p47.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Leukotriene B4-d4, 25 µg | sc-221844 | 25 µg | $256.00 | |||
Leukotriene B4-d4, 50 µg | sc-221844A | 50 µg | $651.00 |