Molecular structure of Leu-Enkephalin, CAS Number: 58822-25-6
Leu-Enkephalin (CAS 58822-25-6)
Alternate Names:
[Leu5}-Enkephalin; Tyr-Gly-Gly-Phe-Leu; Dynorphin-(1-5)
Application:
Leu-Enkephalin is an endogenous agonist for the receptors that are stimulated by opiate alkaloids
CAS Number:
58822-25-6
Purity:
≥95%
Molecular Weight:
555.62
Molecular Formula:
C28H37N5O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Leu-enkephalin is an endogenous agonist for the receptors that are stimulated by opiate alkaloids. It has multiple effects on the central nervous system, including the neuroendocrine hypothalamus. Leu-Enkephalin is an activator of MOR and DOR.
Leu-Enkephalin (CAS 58822-25-6) References
- Occurrence of immunoreactive Met- and Leu-enkephalin-like peptides in the ovary of the green frog, Rana esculenta. | Pestarino, M., et al. 1992. Gen Comp Endocrinol. 85: 118-23. PMID: 1563612
- Dynamic space structure of the Leu-enkephalin molecule in DMSO solution. | Vesterman, B., et al. 1989. Biochim Biophys Acta. 998: 204-9. PMID: 2790063
- A re-examination of the localization of immunoreactive dynorphin(1-8), [Leu]enkephalin and [Met]enkephalin in the rat neurohypophysis. | Gaymann, W. and Martin, R. 1987. Neuroscience. 20: 1069-80. PMID: 2885779
- Leu-enkephalin actions on avoidance conditioning are mediated by a peripheral opioid mechanism. | Martinez, JL., et al. 1985. Life Sci. 37: 2345-53. PMID: 3001460
- Leu-enkephalin impairs memory of an appetitive maze response in mice. | Linden, D. and Martinez, JL. 1986. Behav Neurosci. 100: 33-8. PMID: 3513799
- Effect of Leu-Enkephalin Analogue on the Myeloid Compartment of the Blood System in Hypothyroid White Rats under Stress Conditions. | Garmaeva, DV. 2022. Bull Exp Biol Med. 173: 1-4. PMID: 35622244
- Effects of Neonatal Administration of Non-Opiate Analogues of Leu-Enkephalin to Heart Tissue Homeostasis of Prepubertal Albino Rats Exposed to Hypoxia. | Sazonova, EN., et al. 2022. Bull Exp Biol Med. 173: 188-192. PMID: 35737163
- A dynorphinergic pathway of Leu-enkephalin production in rat substantia nigra. | Zamir, N., et al. Nature. 307: 643-5. PMID: 6546413
- Immunocytochemical evidence for the presence of Met-enkephalin and Leu-enkephalin in distinct neurons in the brain of the elasmobranch fish Scyliorhinus canicula. | Vallarino, M., et al. 1994. J Comp Neurol. 347: 585-97. PMID: 7814676
- [Leu]enkephalin enhances active avoidance conditioning in rats and mice. | Janak, PH., et al. 1994. Neuropsychopharmacology. 10: 53-60. PMID: 8179794
- Ontogeny of Leu-enkephalin and beta-endorphin innervation of the preoptic area in male and female rats. | Ge, F., et al. 1993. Brain Res Dev Brain Res. 73: 273-81. PMID: 8353937
- Cardiovascular effects of Leu-enkephalin in the nucleus tractus solitarius of the rat. | Feldman, PD., et al. 1996. Brain Res. 709: 331-36. PMID: 8833772
- Immunocytochemical localization of enkephalins in the brain of the African lungfish, Protopterus annectens, provides evidence for differential distribution of Met-enkephalin and Leu-enkephalin. | Vallarino, M., et al. 1998. J Comp Neurol. 396: 275-87. PMID: 9624584
Inhibitor of:
VIP.Activator of:
C8α, DOR, DOR-1, MOR, and NPFF1 Receptor.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Leu-Enkephalin, 25 mg | sc-394447 | 25 mg | $215.00 |