Leptin, known as the "satiety hormone", is a hormone made by adipose cells that helps to regulate energy balance by inhibiting hunger. Leptin is opposed by the actions of the hormone ghrelin, the "hunger hormone". Both hormones act on receptors in the arcuate nucleus of the hypothalamus to regulate appetite in order to achieve energy homeostasis. In obesity, a decreased sensitivity to leptin occurs, resulting in an inability to detect satiety despite high energy stores.
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Is it possible to use this product in canine tissue?
Asked by: Anonymous
Thank you for your question. This antibody has not been tested for canine use, and can therefore not be warrantied for this use. If you have any further questions, please contact Technical Service.
Answered by: Tech Service
Date published: 2019-10-31
Buenos dias, he adquirido este producto (leptina liofilizada sc-471278) y me preguntaba como disolverla correctamente. Otras leptinas se tienen que disolver en un buffer Tris. ¿¿Esta es igual??
Asked by: Adrian89
Gracias por su pregunta. Nosotros recomendamos disolver sc-471278:Leptin (mouse), (recombinant) con 20 mM Tris-HCl, pH 8.0 con una concentracion final de 1 mg/ml.
Thank you for your question. We recommend dissolving sc-471278:Leptin (mouse), (recombinant) with 20 mM Tris-HCl, pH 8.0 to a final concentration of 1 mg/ml.
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