Leptin (human), (recombinant) CAS: 177404-21-6
MW: ~16000
A key protein used in obesity studies.

Leptin (human), (recombinant) (CAS 177404-21-6)

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Synonym: OB gene product; OB Protein; Obesity Protein; OBS; Obesity factor
Application: A key protein used in obesity studies
CAS Number: 177404-21-6
Molecular Weight: ~16000
* Refer to Certificate of Analysis for lot specific data (including water content).
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Leptin (aka OB protein, or Obesity factor protein) is a 16-kDa peptide hormone secreted from white adipocytes and implicated in the regulation of food intake and energy balance. Leptin provides the key afferent signal from fat cells in the feedback system that controls body fat stores.

Leptin (human), (recombinant) is produced in E.Coli as a single, non-glycosylated, polypeptide chain containing 146 amino acids and having a molecular mass of approximately 16 kDa. The Leptin protein is purified by proprietary chromatographic techniques.

Biological Activity is evidenced by inducing proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor.

Usage :
Lyophilized Leptin protein is stable at room temperature, but should be stored desiccated below 0°C. Reconstituted Leptin is best stored refrigerated at 4°C.
Formulation :
Lyophilized from a concentrated (1mg/ml) solution with 0.0045mM NaHCO3
Appearance :
Lyophilized
Physical State :
Solid
Solubility :
Leptin is very soluble in water and most aqueous buffers below and above the isoelectric point
Storage :
Desiccate at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Download SDS (MSDS)

Certificate of Analysis

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