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Lenperone (CAS 24678-13-5)

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Alternate Names:
4-[4-(4-Fluorobenzoyl)-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone
CAS Number:
24678-13-5
Molecular Weight:
371.42
Molecular Formula:
C22H23F2NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Lenperone is a butyrophenone, and it has some alpha-adrenergic blocking action. Lenperone is known for its potential use in research applications, particularly in the study of biochemical pathways and receptor interactions. By studying lenperone′s interactions with various neurotransmitter receptors, researchers can gain insights into the regulation of these systems. Lenperone′s effect on signal transduction mechanisms, including those mediated by G-protein-coupled receptors or ion channels, can be a focus of research, shedding light on the intricate processes that govern cellular responses to external and internal stimuli.


Lenperone (CAS 24678-13-5) References

  1. Improvement of ocular blood flow with dopamine antagonists on ocular-hypertensive rabbit eyes.  |  Chiou, GC. and Chen, YJ. 1992. Zhongguo Yao Li Xue Bao. 13: 481-4. PMID: 1302433
  2. Functional and morphological changes in the eccrine sweat gland with heat acclimation.  |  Sato, F., et al. 1990. J Appl Physiol (1985). 69: 232-6. PMID: 2203723
  3. Effect of lenperone hydrochloride on gastroesophageal sphincter pressure in healthy dogs.  |  Johnson, SE., et al. 1989. Can J Vet Res. 53: 248-50. PMID: 2565757
  4. Effects of dopamine antagonists injected through vortex veins on intraocular pressure.  |  Chiou, GC., et al. 1989. J Ocul Pharmacol. 5: 281-91. PMID: 2576433
  5. Effects of CSF ANG II and AVP on sweating in the heat-stressed patas monkey.  |  Owen, MD., et al. 1989. J Appl Physiol (1985). 67: 134-40. PMID: 2759937
  6. Determination of lenperone in dog plasma by high-performance liquid chromatography.  |  Osman, MA., et al. 1985. J Chromatogr. 345: 430-5. PMID: 2868021
  7. Organopromoted Selectivity-Switchable Synthesis of Polyketones.  |  Liu, J., et al. 2017. Org Lett. 19: 5593-5596. PMID: 28981291
  8. Intravenous administration of lenperone and glycopyrrolate followed by continuous infusion of sufentanil in dogs: cardiovascular effects.  |  Benson, GJ., et al. 1987. Am J Vet Res. 48: 1372-5. PMID: 2959181
  9. Dose calibration studies of lenperone, a new tranquilizer for dogs, cats and swine.  |  Cloyd, GD. and Gilbert, DL. 1973. Vet Med Small Anim Clin. 68: 344 passim. PMID: 4487932
  10. Preliminary evaluation of a new psychotropic drug, lenperone, in the treatment of acute schizophrenia.  |  Nakra, BR., et al. 1977. Curr Med Res Opin. 4: 529-34. PMID: 559569
  11. Antipsychotic effects, side effects and effective dosis of the butyrophenone lenperone (AHR 2277).  |  Woggon, B., et al. 1977. Int Pharmacopsychiatry. 12: 113-26. PMID: 561037
  12. Prolactin releasing potencies of antipsychotic and related nonantipsychotic compounds in female rats: relation to clinical potencies.  |  Hays, SE., et al. 1980. J Pharmacol Exp Ther. 214: 362-7. PMID: 6104725
  13. Treatment of ocular hypertension and glaucoma with dopamine antagonists.  |  Chiou, GC. 1984. Ophthalmic Res. 16: 129-34. PMID: 6147806

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Lenperone, 50 mg

sc-488528
50 mg
$380.00