Leflunomide 3-Isomer (CAS 61643-23-0)

Leflunomide 3-Isomer, a chemical compound, has been a prominent focus of scientific research, particularly in the field of immunology. In research, this compound has garnered attention for its immunomodulatory properties. Studies have investigated its effects on immune cells, particularly T lymphocytes, which play a central role in immune responses. Leflunomide 3-Isomer has been shown to inhibit the proliferation and activation of T cells through mechanisms that involve interference with de novo pyrimidine synthesis and inhibition of dihydroorotate dehydrogenase, a key enzyme in the pyrimidine biosynthesis pathway. Moreover, research has explored the potential of Leflunomide 3-Isomer in modulating inflammatory responses. By targeting immune cell function and cytokine production, this compound has been studied for its ability to attenuate inflammation in various experimental models. Investigations into the molecular mechanisms underlying its anti-inflammatory effects offer insights into immune regulation. Furthermore, Leflunomide 3-Isomer has been utilized as a tool in basic research to probe the intricacies of immune regulation. Its use in experimental models and cell culture systems has contributed to our understanding of immune cell signaling pathways and gene expression profiles.