Date published: 2025-10-15

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Ledol (CAS 577-27-5)

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Alternate Names:
Ledum camphor; Porschcampho
Application:
Ledol is an antifungal, toxic sesquiterpenoid, which exhibits expectorant and antitussive effects
CAS Number:
577-27-5
Purity:
≥95%
Molecular Weight:
222.37
Molecular Formula:
C15H26O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Ledol is a sesquiterpene found in certain species of the plant genus Ledum. In research, it is often studied for its potential effects on the biochemistry of aromatic compounds in plants. Scientists examine its role in plant defense mechanisms, particularly in how it may contribute to the repellency or toxicity against herbivores and pathogens. Its ecological interactions are also a focus, as understanding ledol′s function can shed light on the evolutionary advantages conferred by secondary metabolites. Moreover, ledol′s impact on the olfactory system and its potential to affect insect behavior is of interest in ecological research studies. Researchers are additionally engaged in characterizing the compound′s volatility and stability to elucidate its contribution to the aroma and preservation properties of plant-derived products.


Ledol (CAS 577-27-5) References

  1. Essential oil from aerial parts of of Betonica grandiflora Willd. from Iran.  |  Yousefi, M., et al. 2012. Nat Prod Res. 26: 146-51. PMID: 21809955
  2. Composition of seed essential oils of Rhododendron tomentosum.  |  Judzentiene, A., et al. 2012. Nat Prod Commun. 7: 227-30. PMID: 22474965
  3. Chemical and biological evaluation of Hypericum maculatum Crantz essential oil.  |  Ethorđević, AS., et al. 2014. Chem Biodivers. 11: 140-9. PMID: 24443434
  4. Composition of the essential oil of the Rhododendron tomentosum Harmaja from Estonia.  |  Raal, A., et al. 2014. Nat Prod Res. 28: 1091-8. PMID: 24716612
  5. CHEMICAL COMPOSITION AND ANTIBACTERIAL ACTIVITY OF SOME MEDICINAL PLANTS FROM LAMIACEAE FAMILY.  |  Kozłowska, M., et al. 2015. Acta Pol Pharm. 72: 757-67. PMID: 26647633
  6. Is a 1,4-Alkyl Shift Involved in the Biosynthesis of Ledol and Viridiflorol?  |  Hong, YJ. and Tantillo, DJ. 2017. J Org Chem. 82: 3957-3959. PMID: 28277661
  7. Cytotoxic Essential Oils from Eryngium campestre and Eryngium amethystinum (Apiaceae) Growing in Central Italy.  |  Cianfaglione, K., et al. 2017. Chem Biodivers. 14: PMID: 28332760
  8. Chemical composition and anti-Acanthamoeba activity of Melaleuca styphelioides essential oil.  |  Albouchi, F., et al. 2017. Exp Parasitol. 183: 104-108. PMID: 29103900
  9. Understorey Rhododendron tomentosum and Leaf Trichome Density Affect Mountain Birch VOC Emissions in the Subarctic.  |  Mofikoya, AO., et al. 2018. Sci Rep. 8: 13261. PMID: 30185795
  10. Toxicity effects of Eriocephalus africanus L. leaf essential oil against some molecularly identified phytopathogenic bacterial strains.  |  Behiry, SI., et al. 2020. Nat Prod Res. 34: 3394-3398. PMID: 30689407
  11. Toxic, Radical Scavenging, and Antifungal Activity of Rhododendron tomentosum H. Essential Oils.  |  Judzentiene, A., et al. 2020. Molecules. 25: PMID: 32260539
  12. Essential oil from halophyte Lobularia maritima: protective effects against CCl4-induced hepatic oxidative damage in rats and inhibition of the production of proinflammatory gene expression by lipopolysaccharide-stimulated RAW 264.7 macrophages.  |  Hsouna, AB., et al. 2019. RSC Adv. 9: 36758-36770. PMID: 35539073
  13. Antidepressant-like Activity of Patchouli Oil var. Tapak Tuan (Pogostemon cablin Benth) via Elevated Dopamine Level: A Study Using Rat Model.  |  Astuti, P., et al. 2022. Pharmaceuticals (Basel). 15: PMID: 35631434
  14. Neuropeltis acuminata (P. Beauv.): Investigation of the Chemical Variability and In Vitro Anti-inflammatory Activity of the Leaf Essential Oil from the Ivorian Species.  |  Kambiré, DA., et al. 2022. Molecules. 27: PMID: 35744884
  15. Chemical composition, in vitro and in silico evaluation of essential oil from Eucalyptus tereticornis leaves for lung cancer.  |  Anju, ., et al. 2023. Nat Prod Res. 37: 1656-1661. PMID: 35938316

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Ledol, 500 mg

sc-396548
500 mg
$87.00

Ledol, 1 g

sc-396548A
1 g
$158.00