apoB Antibody (5D8): sc-80628
- apoB Antibody (5D8) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against purified plasma apoB oxidized wtih MDA of human origin
- recommended for detection of apoB of human origin by ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for apoB Antibody (5D8). This work is in progress.
LDL Antibody (5D8) is a mouse monoclonal IgG1 antibody that detects low density lipoprotein (LDL) in human samples through enzyme-linked immunosorbent assay (ELISA). LDL plays a crucial role in lipid metabolism by transporting cholesterol and triglycerides from the liver and small intestine to various cells and tissues, which is essential for maintaining cellular function and membrane integrity. LDL is synthesized as very low-density lipoprotein (VLDL) and undergoes a transformation where LDL loses triglycerides through the action of lipoprotein lipase, resulting in smaller, denser particles with a higher cholesterol content. This structural change not only enhances LDL′s ability to deliver cholesterol but also influences LDL′s interaction with LDL receptors on cell surfaces, facilitating uptake and subsequent degradation in lysosomes. Elevated LDL levels are associated with serious health conditions such as atherosclerosis, stroke, and peripheral vascular disease, while mutations in LDL receptors can lead to familial hypercholesterolemia, a genetic disorder that significantly increases the risk of premature coronary atherosclerosis. Anti-LDL antibody (5D8) serves as an invaluable tool for researchers studying lipid metabolism and cardiovascular diseases, providing insights into the mechanisms underlying these critical biological processes.
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
apoB Antibody (5D8) | sc-80628 | 100 µg/ml | $322.00 |