Lck Antibody (B-10): sc-166627
- Lck Antibody (B-10) is a mouse monoclonal IgG2b κ, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 1-95 mapping at the N-terminus of Lck of human origin
- recommended for detection of Lck p56 of mouse, rat and human origin by WB, IP, IF and ELISA
- See Lck (3A5): sc-433 for Lck antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG2b BP-HRP is the preferred secondary detection reagent for Lck Antibody (B-10) for WB applications. This reagent is now offered in a bundle with Lck Antibody (B-10) (see ordering information below).
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SEE ALSO...
Lck Antibody (B-10) is a mouse monoclonal IgG2b antibody that detects Lck in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Lck is a crucial member of the Src family of non-receptor tyrosine kinases, which play a vital role in various cellular processes, including T cell activation and signaling. anti-Lck antibody (B-10) is predominantly located in the plasma membrane and cytoplasm of T cells, where Lck is essential for initiating T cell receptor (TCR) signaling upon antigen recognition. This localization is significant because Lck interacts with other signaling molecules, facilitating the phosphorylation of key substrates that propagate the activation signal within the cell. The proper functioning of Lck is critical for T cell development and immune response, and dysregulation of Lck activity has been implicated in various immunological disorders and cancers. Lck monoclonal antibody (B-10) provides valuable insights into T cell signaling pathways and serves as an invaluable tool for researchers studying immune responses and related diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Lck Antibody (B-10) | sc-166627 | 200 µg/ml | $322.00 | |||
Lck Antibody (B-10): m-IgG2b BP-HRP Bundle | sc-548525 | 200 µg Ab; 10 µg BP | $361.00 |