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Lauroyl-DL-carnitine chloride (CAS 14919-37-0)

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Alternate Names:
DL-Lauroylcarnitine chloride
Application:
Lauroyl-DL-carnitine chloride is a Zwitterionic detergent
CAS Number:
14919-37-0
Molecular Weight:
379.97
Molecular Formula:
C19H38NO4•Cl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Lauroyl-DL-carnitine chloride is a zwitterionic acylcarnitine detergent compound that is described to increase the in vivo mucosal absorption of molecules. It has particularly been demonstrated to enhance nasal absorption of salmon calcitonin in rats most effectively of the acylcarnitines tested, and was separately demonstrated to enhance the nasal absorption of human growth hormone in rats.


Lauroyl-DL-carnitine chloride (CAS 14919-37-0) References

  1. Enhanced intestinal absorption of salmon calcitonin (sCT) from proliposomes containing bile salts.  |  Song, KH., et al. 2005. J Control Release. 106: 298-308. PMID: 15979756
  2. The role of citric acid in oral peptide and protein formulations: relationship between calcium chelation and proteolysis inhibition.  |  Welling, SH., et al. 2014. Eur J Pharm Biopharm. 86: 544-51. PMID: 24384069
  3. In Vitro, Ex Vivo and In Vivo Evaluation of Microcontainers for Oral Delivery of Insulin.  |  Jørgensen, JR., et al. 2020. Pharmaceutics. 12: PMID: 31936066
  4. Enhancement of nasal salmon calcitonin absorption by lauroylcarnitine chloride in rats.  |  Kagatani, S., et al. 1996. Pharm Res. 13: 739-43. PMID: 8860430
  5. Nasal Absorption Kinetics Of Human Growth Hormone Enhanced By Acylcarnitines In Rats  |  Seiya Kagatani, et al. 1998. International Journal of Pharmaceutics. 169: 245-253.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Lauroyl-DL-carnitine chloride, 50 mg

sc-280906B
50 mg
$82.00

Lauroyl-DL-carnitine chloride, 250 mg

sc-280906
250 mg
$120.00

Lauroyl-DL-carnitine chloride, 500 mg

sc-280906A
500 mg
$199.00

What is the LDL vs LCC content ratio for lot F1015?

Asked by: SCchem16
Thank you for your question. The compound, sc-280906, is provided as a racemic mixture with a ratio of 1:1. If you have any further questions or concerns, please feel free to contact our Technical Service department by calling 800-457-3801 option 2, emailing scbt@scbt.com, or using the Live Chat function on our website.
Answered by: Tech Service 8
Date published: 2017-01-31
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Rated 5 out of 5 by from Various publications have cited the use of LauroylVarious publications have cited the use of Lauroyl-DL-carnitine chloride to increase the in vivo mucosal absorption of molecules, and has particularly been demonstrated to enhance nasal absorption of salmon calcitonin in rats most effectively of the acylcarnitines tested, and was separately demonstrated to enhance the nasal absorption of human growth hormone in rats. -SCBT Publication Review
Date published: 2015-04-04
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Lauroyl-DL-carnitine chloride is rated 5.0 out of 5 by 1.
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