Molecular structure of Lauric Acid, CAS Number: 143-07-7
Lauric Acid (CAS 143-07-7)
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Alternate Names:
dodecanoic acid
Application:
Lauric Acid is a common saturated fatty acid compound
CAS Number:
143-07-7
Purity:
>98%
Molecular Weight:
200.36
Molecular Formula:
C12H24O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Lauric Acid, a 12 carbon saturated fatty acid, may act to be incorporated into rat hepatocytes at a higher preference to other cellular lipids. Other murine studies have suggested that this compound is a substrate for acylation of certain proteins. Saturated fatty acids have been reported to be essential for biological activities of lipopolysaccharides and have demonstrated the ability to induce expression of COX-2 and NFkappaB (nuclear factor kappaB) activation. Lauric Acid is a substrate of CYP4A11.
Lauric Acid (CAS 143-07-7) References
- Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4. | Lee, JY., et al. 2001. J Biol Chem. 276: 16683-9. PMID: 11278967
- Although it is rapidly metabolized in cultured rat hepatocytes, lauric acid is used for protein acylation. | Rioux, V., et al. 2003. Reprod Nutr Dev. 43: 419-30. PMID: 15005371
- Effects of lauric acid on upper gut motility, plasma cholecystokinin and peptide YY, and energy intake are load, but not concentration, dependent in humans. | Feltrin, KL., et al. 2007. J Physiol. 581: 767-77. PMID: 17331985
- Analysis of gut microbiota and the effect of lauric acid against necrotic enteritis in Clostridium perfringens and Eimeria side-by-side challenge model. | Yang, WY., et al. 2019. PLoS One. 14: e0205784. PMID: 31150394
- Thiolated chitosan-lauric acid as a new chitosan derivative: Synthesis, characterization and cytotoxicity. | Kazemi, MS., et al. 2019. Int J Biol Macromol. 136: 823-830. PMID: 31228504
- Measuring the Antimicrobial Activity of Lauric Acid against Various Bacteria in Human Gut Microbiota Using a New Method. | Matsue, M., et al. 2019. Cell Transplant. 28: 1528-1541. PMID: 31665909
- Undecanoic Acid, Lauric Acid, and N-Tridecanoic Acid Inhibit Escherichia coli Persistence and Biofilm Formation. | Jin, X., et al. 2021. J Microbiol Biotechnol. 31: 130-136. PMID: 33046677
- Lauric Acid versus Palmitic Acid: Effects on Adipose Tissue Inflammation, Insulin Resistance, and Non-Alcoholic Fatty Liver Disease in Obesity. | Saraswathi, V., et al. 2020. Biology (Basel). 9: PMID: 33105887
- Insect Derived Lauric Acid as Promising Alternative Strategy to Antibiotics in the Antimicrobial Resistance Scenario. | Borrelli, L., et al. 2021. Front Microbiol. 12: 620798. PMID: 33717009
- Inhibition of polymicrobial biofilm formation by saw palmetto oil, lauric acid and myristic acid. | Kim, YG., et al. 2022. Microb Biotechnol. 15: 590-602. PMID: 34156757
- Antimicrobial activity of cyanidin-3-O-glucoside-lauric acid ester against Staphylococcus aureus and Escherichia coli. | Li, L., et al. 2022. Food Chem. 383: 132410. PMID: 35182879
- Stabilisation of oleofoams by lauric acid and its glycerol esters. | Qiu, C., et al. 2022. Food Chem. 386: 132776. PMID: 35509162
- Differential modulations of lauric acid and its glycerides on high fat diet-induced metabolic disorders and gut microbiota dysbiosis. | Zhao, M., et al. 2022. Food Res Int. 157: 111437. PMID: 35761677
- Decontamination of water co-polluted by copper, toluene and tetrahydrofuran using lauric acid. | Earnden, L., et al. 2022. Sci Rep. 12: 15832. PMID: 36138091
Activator of:
SCD1.Substrate of:
CYP4A11.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Lauric Acid, 25 g | sc-205367 | 25 g | $30.00 | |||
Lauric Acid, 100 g | sc-205367A | 100 g | $35.00 | |||
Lauric Acid, 250 g | sc-205367B | 250 g | $77.00 |