This polyclonal antibody has been discontinued. See our recommended LATS1 (G-12) monoclonal antibody (sample data shown).
LATS1 Antibody (G-16): sc-12494
- LATS1 Antibody (G-16) is a goat polyclonal IgG; 200 µg/ml
- epitope mapping near the C-terminus of LATS1 of human origin
- Discontinued polyclonal antibody
The Drosophila tumor suppressor protein lats (for large tumor suppressor) is a putative protein kinase that shares homology with three proteins in Neurospora and budding yeast that are involved in cell cycle and growth regulation: S. cerevisiae Dbf2 and Dbf20, and Neurospora cot-1. Mosaic screens in Drosophila have identified the lats gene as a tumor suppressor in this species. The human homolog, designated LATS1, was shown to inhibit tumor growth in lats-deficient Drosophila. Human LATS1 binds to Cdc2 in early mitosis and appears to negatively regulate the kinase activity of Cdc2. LATS1-deficient mice are highly sensitive to carcinogenic treatments and develop soft-tissue sarcomas and ovarian stromal cell tumors, indicating a role for mammalian LATS1 in tumorigenesis.
Ordering Information
LATS1 (G-12): sc-398560 [ Recommended monoclonal replacement for LATS1 (G-16) ]
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
LATS1 Antibody (G-12) | sc-398560 | 200 µg/ml | $322.00 | |||
LATS1 Antibody (G-12): m-IgG Fc BP-HRP Bundle | sc-527789 | 200 µg Ab; 10 µg BP | $361.00 | |||
LATS1 Antibody (G-12): m-IgG1 BP-HRP Bundle | sc-533162 | 200 µg Ab; 20 µg BP | $361.00 | |||
LATS1 Antibody (G-12) AC | sc-398560 AC | 500 µg/ml, 25% agarose | $424.00 | |||
LATS1 Antibody (G-12) HRP | sc-398560 HRP | 200 µg/ml | $322.00 | |||
LATS1 Antibody (G-12) FITC | sc-398560 FITC | 200 µg/ml | $336.00 | |||
LATS1 Antibody (G-12) PE | sc-398560 PE | 200 µg/ml | $349.00 | |||
LATS1 Antibody (G-12) Alexa Fluor® 488 | sc-398560 AF488 | 200 µg/ml | $364.00 | |||
LATS1 Antibody (G-12) Alexa Fluor® 546 | sc-398560 AF546 | 200 µg/ml | $364.00 | |||
LATS1 Antibody (G-12) Alexa Fluor® 594 | sc-398560 AF594 | 200 µg/ml | $364.00 | |||
LATS1 Antibody (G-12) Alexa Fluor® 647 | sc-398560 AF647 | 200 µg/ml | $364.00 | |||
LATS1 Antibody (G-12) Alexa Fluor® 680 | sc-398560 AF680 | 200 µg/ml | $364.00 | |||
LATS1 Antibody (G-12) Alexa Fluor® 790 | sc-398560 AF790 | 200 µg/ml | $364.00 | |||
LATS1 (G-12) Neutralizing Peptide | sc-398560 P | 100 µg/0.5 ml | $69.00 |