Date published: 2026-2-4

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Latanoprost (free acid) (CAS 41639-83-2)

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Application:
Latanoprost (free acid) is an F-series prostaglandin (PG) analog
CAS Number:
41639-83-2
Purity:
≥98%
Molecular Weight:
390.50
Molecular Formula:
C23H34O5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Latanoprost (free acid) is a compound utilized extensively in biochemical and physiological research, particularly in studies related to the regulation of fluid pressure within the eye. It is a prostanoid selective FP receptor agonist that is used to investigate the mechanism of action of prostanoid receptors on intraocular pressure. The free acid form of Latanoprost is often chosen for research due to its enhanced stability for experimental manipulations. Researchers also employ this compound to study the signaling pathways involved in the modulation of aqueous humor outflow in the trabecular meshwork and its impact on ocular hypertension. In addition, Latanoprost (free acid) serves as a reference standard in analytical studies to ensure the accuracy and precision of bioanalytical assays. It is pivotal in understanding the biochemical cascade of events following prostanoid FP receptor activation and their physiological consequences.


Latanoprost (free acid) (CAS 41639-83-2) References

  1. Latanoprost as a new horizon in the medical management of glaucoma.  |  Stjernschantz, J. and Alm, A. 1996. Curr Opin Ophthalmol. 7: 11-7. PMID: 10163315
  2. Latanoprost and cholinergic agonists in combination.  |  Toris, CB., et al. 2002. Surv Ophthalmol. 47 Suppl 1: S141-7. PMID: 12204711
  3. Latanoprost versus combined timolol and dorzolamide.  |  Bron, AM. and Emmerich, KH. 2002. Surv Ophthalmol. 47 Suppl 1: S148-54. PMID: 12204712
  4. Latanoprost and pigmentation.  |  Grierson, I., et al. 2004. Jpn J Ophthalmol. 48: 602-12. PMID: 15592791
  5. A review of the use of latanoprost for glaucoma since its launch.  |  Digiuni, M., et al. 2012. Expert Opin Pharmacother. 13: 723-45. PMID: 22348427
  6. Preservative-free latanoprost eye drops in patients with primary open-angle glaucoma/ocular hypertension.  |  Sanford, M. 2014. Clin Drug Investig. 34: 521-8. PMID: 24895141
  7. Fixed combination netarsudil-latanoprost for the treatment of glaucoma and ocular hypertension.  |  Sinha, S., et al. 2020. Expert Opin Pharmacother. 21: 39-45. PMID: 31663782
  8. [Long-term use of latanoprost in the treatment of glaucoma].  |  Kurysheva, NI. 2020. Vestn Oftalmol. 136: 125-132. PMID: 32366080
  9. Omidenepag Isopropyl Versus Latanoprost in Primary Open-Angle Glaucoma and Ocular Hypertension: The Phase 3 AYAME Study.  |  Aihara, M., et al. 2020. Am J Ophthalmol. 220: 53-63. PMID: 32533949
  10. Latanoprost Quantification in Ocular Implants and Tissues: HPLC-Fluorescence vs HPLC-UV.  |  Soliman, K., et al. 2021. J Chromatogr Sci. 59: 64-70. PMID: 33047781
  11. Latanoprost-loaded phytantriol cubosomes for the treatment of glaucoma.  |  Bessone, CDV., et al. 2021. Eur J Pharm Sci. 160: 105748. PMID: 33567324
  12. Headaches related to latanoprost in open-angle glaucoma.  |  Wang, H., et al. 2021. Clin Exp Optom. 104: 625-633. PMID: 33689660
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Latanoprost (free acid), 1 mg

sc-205364
1 mg
$122.00

Latanoprost (free acid), 5 mg

sc-205364A
5 mg
$422.00

Latanoprost (free acid), 5 mg

sc-205364A-CW
5 mg
$600.00