Molecular structure of Lappaconitine hydrobromide, CAS Number: 97792-45-5
Lappaconitine hydrobromide (CAS 97792-45-5)
Alternate Names:
Allapinine
Application:
Lappaconitine hydrobromide is a selective TTX-sensitive Na+ channel blocker
CAS Number:
97792-45-5
Purity:
≥95%
Molecular Weight:
665.61
Molecular Formula:
C32H44N2O8•HBr
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
This product is a selective blocker of the TTX-sensitive Na+ channels, and does not influence on the activation threshold of Na+ channels.
Lappaconitine hydrobromide (CAS 97792-45-5) References
- X-ray structure analysis of lappaconitine. | Sun, W., et al. 2009. Nat Prod Res. 23: 960-2. PMID: 19521910
- [Effect of lappaconitine hydrobromide on contractility of small intestinal muscle and its mechanism]. | Yu, YQ., et al. 2008. Zhongguo Ying Yong Sheng Li Xue Za Zhi. 24: 40-1, 85. PMID: 21141554
- [The effect of allapinine on the sodium currents of isolated trigeminal ganglion neurons and cardiomyocytes of rats]. | Valeev, AE., et al. 1990. Neirofiziologiia. 22: 201-6. PMID: 2165574
- Pharmacokinetic study of lappaconitine hydrobromide in mice by LC-MS. | Wang, Q., et al. 2011. Yao Xue Xue Bao. 46: 432-7. PMID: 21748973
- Lappaconitine-loaded microspheres for parenteral sustained release: effects of formulation variables and in vitro characterization. | Xu, H., et al. 2011. Pharmazie. 66: 654-61. PMID: 22026119
- Simultaneous determination of lappaconitine hydrobromide and isopropiram fumarate in rabbit plasma by capillary electrophoresis with electrochemiluminescence detection. | Zhou, M., et al. 2012. Electrophoresis. 33: 2577-83. PMID: 22899266
- Separation and characterization of the metabolic products of lappaconitine in rat urine by high-performance liquid chromatography. | Xie, FM., et al. 1990. J Chromatogr. 526: 109-18. PMID: 2341523
- [To the mechanisms of antiarrhythmic action of Allapinine]. | Vakhitova, IuV., et al. 2013. Bioorg Khim. 39: 105-16. PMID: 23844512
- [The Study of Evidence Base for the Use of Lappaconitine Hydrobromide in Patients With Atrial Fibrillation]. | Erlikh, AD. 2016. Kardiologiia. 56: 48-53. PMID: 28294889
- Analysis of Electrophysiological Mechanisms of N-Deacetyllapaconitine Monochlorhydrate, the Main Metabolite of Lappaconitine Hydrobromide. | Tsorin, IB., et al. 2022. Bull Exp Biol Med. 173: 219-223. PMID: 35739330
- Early initiation of anti-relapse antiarrhythmic therapy in patients with atrial fibrillation and flutter after pharmacological cardioversion with refralon. | Gagloeva, DA., et al. 2023. Kardiologiia. 63: 21-27. PMID: 37470730
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Lappaconitine hydrobromide, 10 mg | sc-300905 | 10 mg | $780.00 | |||
Lappaconitine hydrobromide, 100 mg | sc-300905A | 100 mg | $1000.00 |