Molecular structure of Lactulose, CAS Number: 4618-18-2
Lactulose (CAS 4618-18-2)
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Alternate Names:
4-O-beta-D-Galactopyranosyl-D-fructose
Application:
Lactulose is A keto analogue of lactose
CAS Number:
4618-18-2
Molecular Weight:
342.30
Molecular Formula:
C12H22O11
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Lactulose is a keto analogue of lactose. Primary bile acids are converted to carcinogenic secondary bile acids by colonic bacteria when the colonic pH is high. Addition of lactulose to the diet of experimental animals showed a significant fall in small intestinal and colonic pH. Lactulose is also a substrate for preferential growth of Bifidobacterium longum.
Lactulose (CAS 4618-18-2) References
- Lactulose as a marker of intestinal barrier function in pigs after weaning. | Wijtten, PJ., et al. 2011. J Anim Sci. 89: 1347-57. PMID: 21257783
- Lactulose accelerates liver regeneration in rats by inducing hydrogen. | Yu, J., et al. 2015. J Surg Res. 195: 128-35. PMID: 25700936
- Pharmacological inhibition of galectin-1 by lactulose alleviates weight gain in diet-induced obese rats. | Mukherjee, R. and Yun, JW. 2016. Life Sci. 148: 112-7. PMID: 26880535
- Design and application of a lactulose biosensor. | Wu, J., et al. 2017. Sci Rep. 7: 45994. PMID: 28387245
- Lactulose production from efficient isomerization of lactose catalyzed by recyclable sodium aluminate. | Wang, M., et al. 2017. Food Chem. 233: 151-158. PMID: 28530560
- Lactulose decreases neuronal activation and attenuates motor behavioral deficits in hyperammonemic rats. | Mendes, NF., et al. 2017. Metab Brain Dis. 32: 2073-2083. PMID: 28875419
- Lactulose determination in UHT milk by CZE-UV with indirect detection. | de Oliveira Neves, LN., et al. 2018. Food Chem. 258: 337-342. PMID: 29655742
- Lactulose Management of Minimal Hepatic Encephalopathy: A Systematic Review. | Zucker, DM. and Redulla, R. 2019. Gastroenterol Nurs. 42: 84-94. PMID: 30688711
- Lactulose and Melibiose Inhibit α-Synuclein Aggregation and Up-Regulate Autophagy to Reduce Neuronal Vulnerability. | Chen, CM., et al. 2020. Cells. 9: PMID: 32429337
- Use of Lactulose to Treat Hyperammonemia in ICU Patients Without Chronic Liver Disease or Significant Hepatocellular Injury. | Cutler, NS., et al. 2022. J Intensive Care Med. 37: 698-706. PMID: 34098777
- Enzymatic production of lactulose by fed-batch and repeated fed-batch reactor. | Ramírez, N., et al. 2021. Bioresour Technol. 341: 125769. PMID: 34416660
- Lactulose Modulates the Structure of Gut Microbiota and Alleviates Colitis-Associated Tumorigenesis. | Hiraishi, K., et al. 2022. Nutrients. 14: PMID: 35277009
- Combination therapy with rifaximin and lactulose in hepatic encephalopathy: A systematic review and meta-analysis. | Fu, J., et al. 2022. PLoS One. 17: e0267647. PMID: 35471992
- Comparison of diet, lactulose, and metronidazole combinations in the control of pre-surgical clinical signs in dogs with congenital extrahepatic portosystemic shunts. | Serrano, G., et al. 2022. J Vet Intern Med. 36: 1258-1266. PMID: 35633289
- Lactulose in combination with soybean lecithin has a cryoprotective effect on probiotic taxa of bifidobacteria and Lactobacillaceae. | Killer, J., et al. 2023. Lett Appl Microbiol. 76: PMID: 36657381
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Lactulose, 25 g | sc-280893 | 25 g | $219.00 |