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Lactobionic acid (CAS 96-82-2) - chemical structure image
Molecular structure of Lactobionic acid, CAS Number: 96-82-2
Lactobionic acid (CAS 96-82-2) - chemical structure image
Molecular structure of Lactobionic acid, CAS Number: 96-82-2
Molecular structure of Lactobionic acid, CAS Number: 96-82-2

Lactobionic acid (CAS 96-82-2)

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Alternate Names:
4-O-β-D-Galactopyranosyl-D-gluconic acid
Application:
Lactobionic acid is an inhibitor of matrix metalloproteinases
CAS Number:
96-82-2
Purity:
≥97%
Molecular Weight:
358.30
Molecular Formula:
C12H22O12
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Description
Technical Information
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SDS & Certificate of Analysis

Lactobionic acid is an inhibitor of MMP. It is a type of organic acid derived from lactose. It act as an antioxidant and has moisturizing, exfoliating, chelating, and antibiotic properties. Lactobionic acid has been used to modify the surface of biomaterials used in tissue engineering applications. This modification can improve cell adhesion and proliferation, leading to better tissue regeneration.


Lactobionic acid (CAS 96-82-2) References

  1. Surface modification of magnetite nanoparticles using lactobionic acid and their interaction with hepatocytes.  |  Kamruzzaman Selim, KM., et al. 2007. Biomaterials. 28: 710-6. PMID: 17049979
  2. Oxidation of lactose to lactobionic acid by a Microdochium nivale carbohydrate oxidase: kinetics and operational stability.  |  Nordkvist, M., et al. 2007. Biotechnol Bioeng. 97: 694-707. PMID: 17154316
  3. Physiological heterogeneity of Pseudomonas taetrolens during lactobionic acid production.  |  Alonso, S., et al. 2012. Appl Microbiol Biotechnol. 96: 1465-77. PMID: 22777280
  4. Lactobionic acid-modified dendrimer-entrapped gold nanoparticles for targeted computed tomography imaging of human hepatocellular carcinoma.  |  Liu, H., et al. 2014. ACS Appl Mater Interfaces. 6: 6944-53. PMID: 24712914
  5. Lactobionic acid coupled liposomes: an innovative strategy for targeting hepatocellular carcinoma.  |  Bansal, D., et al. 2016. Drug Deliv. 23: 140-6. PMID: 24786484
  6. Multifunctional lactobionic acid-modified dendrimers for targeted drug delivery to liver cancer cells: investigating the role played by PEG spacer.  |  Fu, F., et al. 2014. ACS Appl Mater Interfaces. 6: 16416-25. PMID: 25185074
  7. Targeted delivery of doxorubicin by lactobionic acid-modified laponite to hepatocarcinoma cells.  |  Chen, G., et al. 2015. J Control Release. 213: e34. PMID: 27005154
  8. Simultaneous inhibition of growth and metastasis of hepatocellular carcinoma by co-delivery of ursolic acid and sorafenib using lactobionic acid modified and pH-sensitive chitosan-conjugated mesoporous silica nanocomplex.  |  Zhao, R., et al. 2017. Biomaterials. 143: 1-16. PMID: 28755539
  9. Potential use of ricotta cheese whey for the production of lactobionic acid by Pseudomonas taetrolens strains.  |  De Giorgi, S., et al. 2018. N Biotechnol. 42: 71-76. PMID: 29476816
  10. The antioxidant and prebiotic properties of lactobionic acid.  |  Goderska, K. 2019. Appl Microbiol Biotechnol. 103: 3737-3751. PMID: 30919101
  11. Antibacterial activity and mechanism of lactobionic acid against Staphylococcus aureus.  |  Cao, J., et al. 2019. Folia Microbiol (Praha). 64: 899-906. PMID: 30993549
  12. High-level production and high-yield recovery of lactobionic acid by the control of pH and temperature in fermentation of Pseudomonas taetrolens.  |  Kim, JH., et al. 2020. Bioprocess Biosyst Eng. 43: 937-944. PMID: 32062704
  13. High lactobionic acid production by immobilized Zymomonas mobilis cells: a great step for large-scale process.  |  Carra, S., et al. 2020. Bioprocess Biosyst Eng. 43: 1265-1276. PMID: 32172349
  14. Purification and Characterization of a Malate:Quinone Oxidoreductase from Pseudomonas taetrolens Capable of Producing Valuable Lactobionic Acid.  |  Oh, YR., et al. 2020. J Agric Food Chem. 68: 13770-13778. PMID: 33166455
  15. Inhibitory effects of lactobionic acid on Vibrio parahaemolyticus planktonic cells and biofilms.  |  Fan, Q., et al. 2022. Food Microbiol. 103: 103963. PMID: 35082080

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Lactobionic acid, 100 g

sc-221826
100 g
$240.00

Lactobionic acid, 500 g

sc-221826A
500 g
$376.00

What is the appearance of the compound?

Asked by: two2igm05
Thank you for your question. The compound, sc-221826, is provided as a white to off-white crystalline powder. If you have any further questions or concerns, please feel free to contact our Technical Service department by calling 800-457-3801 option 2, emailing scbt@scbt.com, or using the Live Chat function on our website.
Answered by: Tech Service 8
Date published: 2018-03-06
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Rated 5 out of 5 by from Mukherjee et alMukherjee et al. (PubMed ID 26116537) found that lactobionic acid reduced lipogenic capacity of adipocytes by reducing the expression of adipogenic transcription factors via galectin-1 inhibition in obese rats. -SCBT Publication Review
Date published: 2015-05-27
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Lactobionic acid is rated 5.0 out of 5 by 1.
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